Noma, a neglected disease: prevention is better than cure
- PMID: 35906973
- DOI: 10.1097/MOO.0000000000000819
Noma, a neglected disease: prevention is better than cure
Abstract
Purpose of review: There is a need for concerted effort to increase Global awareness about noma (cancrum oris). This paper aims to summarize the recent literature on noma and provide suggestions that could be implemented to raise awareness about this neglected disease.
Recent findings: Noma has been recognized, diagnosed and reported for centuries. Despite significant progress in scientific methods over time, the published literature on noma has predominantly been of low level clinical and scientific evidence. Recent studies have reported on noma's global distribution and its predisposing risk factors, its treatment, its knowledge and beliefs and has included a number of literature reviews. Noma cases are being reported from an increasingly diverse set of geographical locations.
Summary: Noma has largely been neglected in the research sphere. Noma is a preventable disease and its progression can be halted if patients are recognized and treated in the early stages of disease. Treatment for late stage noma survivors remains complex and time consuming, requiring substantial human and financial resources most commonly not achieving functional and cosmetic anatomy. The ultimate aim is therefore prevention, initiatives should be integrated into existing health programs.
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
Similar articles
-
Noma (cancrum oris): A scoping literature review of a neglected disease (1843 to 2021).PLoS Negl Trop Dis. 2021 Dec 14;15(12):e0009844. doi: 10.1371/journal.pntd.0009844. eCollection 2021 Dec. PLoS Negl Trop Dis. 2021. PMID: 34905547 Free PMC article.
-
[Noma/Cancrum oris: a neglected disease].Rev Esp Quimioter. 2015 Oct;28(5):225-34. Rev Esp Quimioter. 2015. PMID: 26437752 Review. Spanish.
-
Understanding noma: WHO's recognition and the path forward in global health.Trans R Soc Trop Med Hyg. 2024 Sep 2;118(9):625-628. doi: 10.1093/trstmh/trae031. Trans R Soc Trop Med Hyg. 2024. PMID: 38708708
-
Is noma a neglected/overlooked tropical disease?Trans R Soc Trop Med Hyg. 2022 Oct 2;116(10):884-888. doi: 10.1093/trstmh/trac043. Trans R Soc Trop Med Hyg. 2022. PMID: 35576473 Free PMC article.
-
Noma: A Neglected Area for Research.J Dent Res. 2022 Nov;101(12):1424-1429. doi: 10.1177/00220345221100399. Epub 2022 May 27. J Dent Res. 2022. PMID: 35622443
Cited by
-
Systematic scoping review of the noma evidence landscape: current knowledge and gaps.BMJ Glob Health. 2025 Jul 31;10(7):e018023. doi: 10.1136/bmjgh-2024-018023. BMJ Glob Health. 2025. PMID: 40744672 Free PMC article.
-
Prevalence and associated risk factors for noma in Nigerian children: a systematic review and meta-analysis.BMC Oral Health. 2024 Jun 12;24(1):685. doi: 10.1186/s12903-024-04451-y. BMC Oral Health. 2024. PMID: 38867180 Free PMC article.
-
Surgical Procedures, Complications, and Durations in Patients with Noma Disease: A Cross-sectional Study.Plast Reconstr Surg Glob Open. 2023 Dec 19;11(12):e5496. doi: 10.1097/GOX.0000000000005496. eCollection 2023 Dec. Plast Reconstr Surg Glob Open. 2023. PMID: 38115840 Free PMC article.
References
-
- Ritchie P. Observations on the inflammations of the mouth in children, with an illustrative case. Trans Edinburgh Obstet Soc 1871; 2:418–435.
-
- Marck K. Cancrum oris and noma: Some etymological and historical remarks. Br J Plast Surg 2003; 56:524–527.
-
- World Health Organization Regional Office for Africa. Information brochure for early detection and management of noma. 2017. Available at: https://apps.who.int/iris/handle/10665/254579 .
-
- Falkler W, Enwonwu C, Idigbe E. Isolation of fusobacterium necrophorium from cancrum oris [noma]. Am J Trop Med Hyg 1999; 60:150–156.
-
- Falkler W, Enwonwu C, Idigbe E. Microbiological understandings and mysteries of noma [cancrum oris]. Oral Dis 1999; 5:150–155.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials