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Case Reports
. 2022 Oct;121(10):3007-3011.
doi: 10.1007/s00436-022-07607-3. Epub 2022 Jul 30.

First report of rodent-adapted Cryptosporidium wrairi in an immunocompetent child, Spain

Carolina Hernández-Castro #  1   2 , Alejandro Dashti #  1 , Pamela Carolina Köster  1 , Begoña Bailo  1 , Andrea López  3 , María Teresa Llorente  3 , David González-Barrio  1 , Sergio Sánchez  4 , David Carmena  5   6
Affiliations
Case Reports

First report of rodent-adapted Cryptosporidium wrairi in an immunocompetent child, Spain

Carolina Hernández-Castro et al. Parasitol Res. 2022 Oct.

Abstract

Cryptosporidiosis is a leading cause of childhood diarrhoea. Two species, Cryptosporidium hominis and Cryptosporidium parvum, are responsible for most confirmed cases globally. Close contact with pet animals can be an unnoticed source of children infections. We describe a case of infection by rodent-adapted Cryptosporidium wrairi in a 22-month-old immunocompetent toddler with no clinical manifestations in close contact with a pet guinea pig and poor personal hygiene practices in Majadahonda (Madrid, Spain). Attempts to determine the C. wrairi genotype family at the 60-kDa glycoprotein marker failed repeatedly. This is the first description of C. wrairi in a human host. Although a spurious infection cannot be completely ruled out, data presented here suggest that C. wrairi can be transmitted zoonotically.

Keywords: Children; Cryptosporidiosis; Cryptosporidium wrairi; Spain; Transmission; Zoonosis.

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