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Case Reports
. 2022 Oct:117:104087.
doi: 10.1016/j.jevs.2022.104087. Epub 2022 Jul 29.

Equine Gastric Squamous Cell Carcinoma in a Friesian Stallion

Paola Straticò  1 , Elisabetta Razzuoli  2 , Jasmine Hattab  1 , Giulia Guerri  3 , Gianluca Celani  1 , Adriana Palozzo  1 , Daniele Bonanni  4 , Floriana Fruscione  2 , Vincenzo Varasano  1 , Lucio Petrizzi  1 , Giuseppe Marruchella  1
Affiliations
Case Reports

Equine Gastric Squamous Cell Carcinoma in a Friesian Stallion

Paola Straticò et al. J Equine Vet Sci. 2022 Oct.

Abstract

A 7-year-old Friesian stallion with a history of oesophageal stenosis, weight loss, inappetence, and recurrent hyperthermia was referred for gastroscopy. The stomach mucosa surrounding the oesophageal opening showed a large, necrotic, and ulcerated mass. On post-mortem examination, a very large, cauliflower-like neoplasm was seen, affecting non-glandular gastric mucosa. Nodular lesions were observed, scattered on the omentum, the spleen, and the liver. Microscopic findings allowed the diagnosis of gastric squamous cell carcinoma with abdominal metastasis. Biomolecular investigations demonstrated the presence of EcPV-2 genes in neoplastic lesions, thus supporting the role of EcPV-2 in the ethiology of equine gastric cancer.

Keywords: Endoscopy; Horse; Neoplasia; Oesophageal stenosis; Stomach.

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Conflict of interest statement

Conflict of Interest statement We declare that none of the authors (please, see the list below) has affiliation with any organization with a direct or indirect financial interest in the subject matter discussed in the manuscript. ▪ Paola Straticò ▪ Elisabetta Razzuoli ▪ Jasmine Hattab ▪ Giulia Guerri ▪ Gianluca Celani ▪ Adriana Palozzo ▪ Daniele Bonanni ▪ Floriana Fruscione ▪ Vincenzo Varasano ▪ Lucio Petrizzi ▪ Giuseppe Marruchella. Sincerely, Paola Straticò, PhD, DVM University of Teramo, Faculty of Veterinary Medicine Loc.. Piano D'Accio 64100 - Teramo (ITALY) pstratico@unite.it.

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