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Review
. 2022 Jul 20:2022:2121993.
doi: 10.1155/2022/2121993. eCollection 2022.

The Regulatory Effects of MicroRNAs on Tumor Immunity

Yan Lu  1 , Muwen Deng  2   3 , Kang Wang  2   3 , Yuanhong Peng  2   3 , Manzhao Ouyang  2   3
Affiliations
Review

The Regulatory Effects of MicroRNAs on Tumor Immunity

Yan Lu et al. Biomed Res Int. .

Abstract

MicroRNAs are endogenous noncoding small RNAs that posttranscriptionally regulate the expressions of their target genes. Accumulating research shows that miRNAs are crucial regulators of immune cell growth and antitumor immune response. Studies on miRNAs and tumors primarily focus on the tumor itself. At the same time, relatively few studies on the indirect regulatory effects of miRNAs in the development of tumors are achieved by affecting the immune system of tumor hosts and altering their immune responses. This review discusses the influence of miRNAs on the antitumor immune system.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
miRNA biogenesis.
Figure 2
Figure 2
miRNA affects the polarization of macrophages.
Figure 3
Figure 3
miRNAs participate in the immune responses.
See this image and copyright information in PMC

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