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Review
. 2022 May 19:3:100140.
doi: 10.1016/j.crmicr.2022.100140. eCollection 2022.

Global distribution of animal sporotrichosis: A systematic review of Sporothrix sp. identified using molecular tools

Debora Salgado Morgado  1   2 , Rodolfo Castro  3   4 , Marcelo Ribeiro-Alves  5 , Danielly Corrêa-Moreira  2   6 , Julio Castro-Alves  7   8 , Sandro Antonio Pereira  1 , Rodrigo Caldas Menezes  1 , Manoel Marques Evangelista Oliveira  6   9
Affiliations
Review

Global distribution of animal sporotrichosis: A systematic review of Sporothrix sp. identified using molecular tools

Debora Salgado Morgado et al. Curr Res Microb Sci. .

Abstract

Sporotrichosis is a subcutaneous mycosis caused by thermodimorphic fungi of the genus Sporothrix. The phenotypic and genotypic differences of the isolates within the genus Sporothrix have been associated with their geographic distribution, virulence capacity, or clinical manifestation of sporotrichosis. Therefore, it is crucial to identify the causative agent of sporotrichosis. However, there are few case reports and studies in animals compared to those in humans, despite the substantial increase in the number of cases of sporotrichosis by zoonotic transmission, especially in endemic areas. Considering the epidemiological importance, taxonomic evolution and worldwide distribution of these fungi in the last decade, there is interest in identifying the species of the genus Sporothrix in different regions of the world. This study aimed to analyze the geographic distribution of animal sporotrichosis in the world, caused by pathogenic species identified by use of molecular tools. This systematic review of articles from 2007 to 2021 analyzed the geographic distribution of species that cause sporotrichosis in cats, dogs and other animals. It demonstrated that the most identified species were S. brasiliensis, isolated from cats in Brazil and S. schenckii isolated from cats in Malaysia. We show the lack of studies in global areas and reinforce the need to use molecular tools to identify and monitor potential pathogens.

Keywords: Cat diseases; Dog diseases; Sporothrix; Sporotrichosis; Systematic review.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Image, graphical abstract
Graphical abstract
Fig 1
Fig. 1
PRISMA 2020, flow diagram of the search and inclusion process in the study.
Fig 2
Fig. 2
Case reports of animal sporotrichosis all over the world. The sizes of the graphs represent quantitative differences of the cases, in highest number in South America, followed by Asia and Europe. North America and Africa reported the same number of cases and Central America was the continent with fewest reported cases. Only one case was reported in Oceania.
See this image and copyright information in PMC

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