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Review
. 2022;28(5):135.
doi: 10.1007/s10989-022-10437-7. Epub 2022 Jul 27.

The Updated Review on Plant Peptides and Their Applications in Human Health

Saiprahalad Mani  1 , Smruti B Bhatt  1 , Vinduja Vasudevan  1 , Dhamodharan Prabhu  2 , Sundararaj Rajamanikandan  2 , Palaniyandi Velusamy  2 , Palaniappan Ramasamy  2 , Pachaiappan Raman  1
Affiliations
Review

The Updated Review on Plant Peptides and Their Applications in Human Health

Saiprahalad Mani et al. Int J Pept Res Ther. 2022.

Abstract

Biologically active plant peptides, consisting of secondary metabolites, are compounds (amino acids) utilized by plants in their defense arsenal. Enzymatic processes and metabolic pathways secrete these plant peptides. They are also known for their medicinal value and have been incorporated in therapeutics of major human diseases. Nevertheless, its limitations (low bioavailability, high cytotoxicity, poor absorption, low abundance, improper metabolism, etc.) have demanded a need to explore further and discover other new plant compounds that overcome these limitations. Keeping this in mind, therapeutic plant proteins can be excellent remedial substitutes for bodily affliction. A multitude of these peptides demonstrates anti-carcinogenic, anti-microbial, anti-HIV, and neuro-regulating properties. This article's main aim is to list out and report the status of various therapeutic plant peptides and their prospective status as peptide-based drugs for multiple diseases (infectious and non-infectious). The feasibility of these compounds in the imminent future has also been discussed.

Keywords: Anti-HIV; Anti-carcinogenic; Antifungal; Peptide-based drugs; Ribosomal-Inactivating Proteins (RIPs); Therapeutic plant peptides.

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Conflict of interest statement

Conflict of interestThe authors have no conflicts of interest to declare that are relevant to the content of this article.

Figures

Fig. 1
Fig. 1
Schematic representation of plants peptides displaying various therapeutic properties
See this image and copyright information in PMC

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