Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jul 27;10(7):e6158.
doi: 10.1002/ccr3.6158. eCollection 2022 Jul.

Collodion phenotype remains a challenge for neonatologists: A rare case of self-healing collodion baby

Nikolina Zdraveska  1 , Aco Kostovski  1 , Aspazija Sofijanova  1 , Snezana Jancevska  2 , Katerina Damevska  3
Affiliations
Case Reports

Collodion phenotype remains a challenge for neonatologists: A rare case of self-healing collodion baby

Nikolina Zdraveska et al. Clin Case Rep. .

Abstract

We report a unique case of self-healing collodion baby (CB) that was successfully managed despite the risk of potentially serious complications. Self-healing CB is a rare and distinct outcome of collodion phenotype occurring in approximately 10% of the cases. The outcome depends on the initial assessment and adequate multidisciplinary approach.

Keywords: collodion baby; congenital ichthyosis; cornification; membrane; neonatal.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Parchment‐like membrane covering the whole body, with multiple fissures and scaling
FIGURE 2
FIGURE 2
Excess of scales around the mouth gave the typical fish‐like mouth appearance. Bilateral ectropion, flattening of the nose, and ears overlaying
FIGURE 3
FIGURE 3
Clawed‐hand deformity
FIGURE 4
FIGURE 4
Diagnostic workup in a collodion baby
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Van Gysel D, Lijnen RL, Moekti SS, de Laat PC, Oranje AP. Collodion baby: a follow‐up study of 17 cases. J Eur Acad Dermatol Venereol. 2002;16(5):472‐475. - PubMed
    1. Judge M. In: Harper J, Oranje A, Prose N, eds. “Collodion Baby and Harlequin Ichthyosis,” in Textbook of Pediatric Dermatology. 2nd ed. Blackwell; 2006:118‐125.
    1. Rimoin L, Graham JM. Ichthyotic skin disorders in the neonate. Clin Pediatr (Phila). 2012;51(8):796‐800. - PMC - PubMed
    1. Chung M, Pittenger J, Tobin S, Chung A, Desai N. Expedient treatment of a collodion baby. Case Rep Dermatol Med. 2011;2011:803782. - PMC - PubMed
    1. Harting M, Brunetti‐Pierri N, Chan CS, et al. Self‐healing collodion membrane and mild nonbullous congenital Ichthyosiform erythroderma due to 2 novel mutations in the ALOX12B gene. Arch Dermatol. 2008;144(3):351‐356. - PubMed

Publication types

LinkOut - more resources