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. 2022 Aug 2;11(1):29.
doi: 10.1186/s13741-022-00261-4.

Postoperative fasting is associated with longer ICU stay in oncologic patients undergoing elective surgery

Caroline Fachini  1 , Claudio Z Alan  2 , Luciana V Viana  3
Affiliations

Postoperative fasting is associated with longer ICU stay in oncologic patients undergoing elective surgery

Caroline Fachini et al. Perioper Med (Lond). .

Abstract

Background: Cancer patients present nutritional and complications risks during the postoperative period. Fasting contributes to surgical catabolic damage. This study evaluates the consequence of fasting time on the surgical outcomes of cancer patients undergoing elective surgeries.

Methods: Prospective cohort, evaluating two categories of patients according to postoperative fasting: less than or greater than 24 h.

Outcomes: Hospitalization time, 28-day mortality, ICU stay and infection rates.

Discussion: We included 109 patients (57% men, 60 ± 15 years, BMI: 26 ± 5 kg/m2, SAPS3 43 ± 12), hepatectomy was the most frequent surgery (13.8%), and colon and rectum were the most common neoplasia (18.3%). The ICU stay was longer in postoperative fasting > 24 h (5.5 [4-8.25] vs. 3 [2-5] days, p < 0.001). Fasting > 24 h persisted as a risk factor for longer length of stay (LOS) in the ICU after adjustments. There were no differences in the mortality analysis within 28 days and total hospitalization time between groups. A tendency to experience more infections was observed in patients who fasted > 24 h (34.8% vs. 16.3%, p = 0.057). Onset of diet after the first 24 h postoperatively was a risk factor for longer ICU stay in cancer patients who underwent major surgeries.

Keywords: Fasting; Length of stay; Surgical oncology.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart of patients included in the study
See this image and copyright information in PMC

References

    1. Arends J, Baracos V, Bertz H, Bozzetti F, Calder PC, Deutz NEP, et al. ESPEN expert group recommendations for action against cancer-related malnutrition. Clin Nutr. 2017;36(5):1187–1196. doi: 10.1016/j.clnu.2017.06.017. - DOI - PubMed
    1. Assis MC, Silveira CR, Beghetto MG, Mello E. Is duration of postoperative fasting associated with infection and prolonged length of stay in surgical patients? Nutr Hosp. 2014;30(4):919–926. - PubMed
    1. Assis MCS, Silveira CRM, Beghetto MG, Mello ED. ¿Duracion del ayuno postoperatorio se asocia con la infeccion y la estancia prolongada en pacientes quirurgicos? Nutr Hosp. 2014;30(4):919–926. - PubMed
    1. Baker JP, Detsky AS, Wesson DE, et al. Nutritional assessment: a comparison of clinical judgment and objective measurements. N Engl J Med. 1982;306(16):969–972. doi: 10.1056/NEJM198204223061606. - DOI - PubMed
    1. Berger MM, Chiolero RL. Enteral nutrition and cardiovascular failure: from myths to clinical practice. J Parenter Enteral Nutr. 2009;33(6):702–709. doi: 10.1177/0148607109341769. - DOI - PubMed