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. 2022 Jul 23:2022:8234769.
doi: 10.1155/2022/8234769. eCollection 2022.

Application Value of Nutrition Support Team in Chemotherapy Period of Colon Cancer Based on Internet Multidisciplinary Treatment Mode

Jianfeng Chen  1 , Bo Wang  1 , Xiaobin Yin  1 , Qifei Liang  1 , Yucheng Li  1 , Xingjiang Xie  1 , Xuehui Zeng  1
Affiliations

Application Value of Nutrition Support Team in Chemotherapy Period of Colon Cancer Based on Internet Multidisciplinary Treatment Mode

Jianfeng Chen et al. Comput Math Methods Med. .

Abstract

Objective: To explore the application value of the nutrition support team in chemotherapy period of colon cancer based on the internet multidisciplinary treatment mode.

Methods: For the method of retrospective study, 90 patients with colon cancer admitted to our hospital from August 2018 to August 2020 were selected as the study subjects. They were equally divided into the experimental group (n = 45) and the control group (n = 45) according to the order of initials and the method of parity group. The control group was given conventional nutrition support, and the experimental group was given the nutrition support under the internet multidisciplinary treatment mode. The serum tumor marker levels (CEA and CA19-9), immune function indexes, nutrition indicators, and the incidence of adverse reactions were compared between the two groups before and after intervention.

Results: The serum tumor marker levels in the experimental group after intervention were significantly lower than those in the control group (P < 0.001). The immune function indexes in the experimental group after intervention were significantly better than those in the control group (P < 0.001). The nutrition indicators in the experimental group after intervention were significantly better than those in the control group (P < 0.001). The incidence of gastrointestinal adverse reactions above grade 2 in the experimental group was significantly lower than that in the control group (P < 0.05). There were 20 patients with myelosuppression, 2 patients with neurotoxicity, and 1 patient with hand and foot syndrome in the experimental group, while 22 patients with myelosuppression, 4 patients with neurotoxicity, and 2 patients with hand and foot syndrome in the control group, with no significant difference in the incidence of adverse reactions between the two groups (P > 0.05).

Conclusion: The nutrition support team under the internet multidisciplinary treatment mode can improve the immune function of chemotherapy patients with colon cancer and enhance their nutritional level, thereby reducing the incidence of adverse reactions and improving the chemotherapy effects.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Serum tumor marker levels (x̅±s). (a) CEA level. (b) CA19-9 level. (c) CA72-4 level.
Figure 2
Figure 2
Levels of immune function indexes (x̅±s). (a) Levels of CD4+, CD8+, and CD4+/CD8+ before intervention. (b) Levels of CD4+, CD8+, and CD4+/CD8+ after intervention. (c) Levels of Treg, Th9, and Th17 before intervention. (d) Levels of Treg, Th9, and Th17 after intervention.
Figure 3
Figure 3
Levels of nutrition indicators (x̅±s). (a) Body weight. (b) TP level. (c) ALB level. (d) Hb level.
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