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Review
. 2022 Sep 1;33(5):394-398.
doi: 10.1097/ICU.0000000000000869.

The American Academy of Ophthalmology IRIS Registry (Intelligent Research In Sight): current and future state of big data analytics

Suzann Pershing  1   2 , Flora Lum  3
Affiliations
Review

The American Academy of Ophthalmology IRIS Registry (Intelligent Research In Sight): current and future state of big data analytics

Suzann Pershing et al. Curr Opin Ophthalmol. .

Abstract

Purpose of review: To describe the drivers, development, and current state of the American Academy of Ophthalmology IRIS Registry (Intelligent Research In Sight), and analytics involving deidentified aggregate IRIS Registry data.

Recent findings: The IRIS Registry has a core mission of quality improvement and reporting. In addition, analytic projects performed to date have included characterizing patient populations and diseases, incidence, and prevalence; clinical outcomes and complications; risk factors and effect modifiers; practice patterns; and trends over time. Pipeline projects include application of artificial intelligence and machine learning approaches for predictive modeling and analytics, disease mapping, detecting patterns and identifying cohorts, and optimizing treatment based on patient-specific characteristics.

Summary: The IRIS Registry is the nation's largest single specialty clinical registry, with unique data elements specific to ophthalmology. It offers a wealth of opportunities involving big data analytics, including traditional inferential statistics as well as machine learning and artificial intelligence approaches scalable on massive amounts of data.

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Conflict of interest statement

Conflicts of interest

S.P. is a consultant for Acumen, LLC (Burlingame, CA) and Verana Health (San Francisco, CA).

References

    1. Sommer A, Abbott RL, Lum F, Hoskins HD. PPPs - twenty years and counting. Ophthalmology 2008; 115:2125–2126. - PubMed
    1. Lum F, Schein O, Schachat AP, et al. Initial two years of experience with the AAO National Eyecare Outcomes Network (NEON) cataract surgery database. Ophthalmology 2000; 107:691–697. - PubMed
    1. Lum F, Schachat AP, Jampel HD. The development and demise of a cataract surgery database. Jt Comm J Qual Improv 2002; 28:108–114. - PubMed
    1. Shahian DM, Jacobs JP, Edwards FH, et al. The Society of Thoracic Surgeons National Database. Heart 2013; 99:1494–1501. - PubMed
    1. Brindis RG, Fitzgerald S, Anderson HV, et al. The American College of Cardology-National Cardiovascular Data Registry (ACC-NCDR): building a national clinical data repository. J Am Coll Cardiol 2001; 37:2240–2245. - PubMed