Current concepts in the management of childhood myopia
- PMID: 35918919
- PMCID: PMC9672783
- DOI: 10.4103/ijo.IJO_2098_21
Current concepts in the management of childhood myopia
Abstract
Myopia or short-sightedness is an emerging pandemic affecting more than 50% population in South-Asian countries. It is associated with several sight-threatening complications, such as retinal detachment and choroidal neovascularization, leading to an increased burden of visual impairment and blindness. The pathophysiology of myopia involves a complex interplay of numerous environmental and genetic factors leading to progressive axial elongation. Environmental factors such as decreased outdoor activity, reduced exposure to ambient light, strenuous near work, and role of family history of myopia have been implicated with increased prevalence of this refractive error. While multiple clinical trials have been undertaken to devise appropriate treatment strategies and target the modifiable risk factors, there is no single treatment modality with ideal results; therefore, formulating a comprehensive approach is required to control the myopia epidemic. This review article summarizes the epidemiology, dynamic concepts of pathophysiology, and evolution of the treatment modalities for myopia such as pharmacological (atropine and other agents) and optical methods (spectacles, contact lenses, and orthokeratology).
Keywords: Atropine; childhood myopia; contact lenses; orthokeratology; refractive error; spectacles.
Conflict of interest statement
None
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Comment in
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Commentary: Curbing myopia progression: The way forward.Indian J Ophthalmol. 2022 Aug;70(8):2816-2817. doi: 10.4103/ijo.IJO_706_22. Indian J Ophthalmol. 2022. PMID: 35918920 Free PMC article. No abstract available.
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References
-
- Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, et al. Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology. 2016;123:1036–42. - PubMed
-
- Mutti DO. Hereditary and environmental contributions to emmetropization and myopia. Optom Vis Sci. 2010;87:255–9. - PubMed
-
- Naidoo KS, Leasher J, Bourne RR, Flaxman SR, Jonas JB, Keeffe J, et al. Global vision impairment and blindness due to uncorrected refractive error, 1990-2010. Optom Vis Sci Off Publ Am Acad Optom. 2016;93:227–34. - PubMed
-
- Bourne RR, Stevens GA, White RA, Smith JL, Flaxman SR, Price H, et al. Causes of vision loss worldwide, 1990-2010:A systematic analysis. Lancet Glob Health. 2013;1:e339–49. - PubMed
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