Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec 18;11(2):85-93.
doi: 10.15171/japid.2019.014. eCollection 2019.

Effect of one and two sessions of antimicrobial photodynamic therapy on clinical and microbial outcomes of non-surgical management of chronic periodontitis: A clinical study

Ardeshir Lafzi  1 , Seyed Masoud Mojahedi  2 , Mahdieh Mirakhori  3 , Maryam Torshabi  4 , Mahdi Kadkhodazadeh  1 , Reza Amid  1 , Mohamadjavad Karamshahi  5 , Mohammad Arbabi  6 , Hasti Torabi  6
Affiliations

Effect of one and two sessions of antimicrobial photodynamic therapy on clinical and microbial outcomes of non-surgical management of chronic periodontitis: A clinical study

Ardeshir Lafzi et al. J Adv Periodontol Implant Dent. .

Abstract

Background: This study aimed to compare the effect of one and two sessions of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) on clinical and microbial parameters in patients with chronic periodontitis.

Methods: This study was conducted on 20 patients. The dental quadrants of patients were randomly assigned to SRP at baseline (group 1), SRP at baseline and one month (group 2), SRP plus aPDT at baseline (group 3) and SRP plus aPDT at baseline and one month (group 4). Probing depth (PD), clinical attachment level (CAL) gain, and bleeding on probing (BoP) were measured at baseline, and one and three months later. F. nucleatum counts were determined by PCR. ANOVA was used for the comparison of these variables between the groups.

Results: In all the groups, PD reduction and CAL gain increased significantly at 1- and 3-month intervals compared to baseline (P=0.001). At three months, the difference in PD between groups 1 and 3 was statistically significant (P=0.014). CAL gain between groups 2 and 4 at one month (P=0.016) and three months (P=0.001) wasstatistically significant. Reduction in F. nucleatum counts was not significant between the four study groups (P>0.05).

Conclusion: A combination of two sessions of aPDT and SRP could improve CAL gain; however, further long-term studies are necessary in this regard.

Keywords: Chronic periodontitis; non-surgical periodontal therapy; photodynamic therapy; scaling and root planing.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict(s) of interest related to the publication of this work.

Similar articles

See all similar articles

Cited by

References

    1. Greenstein G. Periodontal response to mechanical non‐surgical therapy: A review. J Periodontol. 1992;63:118–30. - PubMed
    1. Braun A, Dehn C, Krause F, Jepsen S. Short-term clinical effects of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial. J Clin Periodontol. 2008;35:877–84. - PubMed
    1. Bonito AJ, Lux L, Lohr KN. Impact of local adjuncts to scaling and root planing in periodontal disease therapy: a systematic review. J Periodontol. 2005;76:1227–36. - PubMed
    1. Kinney KK. Treatment of infections caused by antimicrobial-resistant gram-positive bacteria. Am J Med Sci. 2010;340:209–217. - PubMed
    1. Jepsen K, Jepsen S. Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis. Periodontol 2000. 2016;71:82–112. - PubMed

LinkOut - more resources