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. 2022 Jun 30;27(2):165-171.
doi: 10.3746/pnf.2022.27.2.165.

FiberCreme as a Functional Food Ingredient Reduces Hyperlipidemia and Risk of Cardiovascular Diseases in Subjects with Hyperlipidemia

Affiliations

FiberCreme as a Functional Food Ingredient Reduces Hyperlipidemia and Risk of Cardiovascular Diseases in Subjects with Hyperlipidemia

Sunarti et al. Prev Nutr Food Sci. .

Abstract

FiberCreme is a commercial nondairy creamer made with isomalto-oligosaccharides (IMO) that is a source of dietary fiber. A study showed that IMO could decrease cholesterol (CH) and triglycerides, which are factors related to the risk of cardiovascular diseases and insulin resistance. This study evaluated FiberCreme's ability as a functional food ingredient to reduce CH and the risk of cardiovascular diseases in subjects with hyperlipidemic. This controlled clinical study trial involved 53 (23∼57 years old) subjects with borderline high CH (>190 mg/dL) or triglycerides (>150 mg/dL) or both, who were divided into FiberCreme and control groups. The participant received 86 g of cookies daily for 4 weeks. The FiberCreme and control groups consumed FiberCreme-containing cookies and cookies with coconut cream with 5.78% and 4.69% fibers, respectively. Lipid profile, anthropometry, body composition, and food intake were also measured. Data analysis was performed using SPSS v.25. This study suggests that FiberCreme cookies can significantly reduce CH, triglycerides, and cardiac risk ratio scores.

Keywords: FiberCreme; cardiac risk ratio scores; cholesterol; isomalto-oligosaccharides; triglyceride.

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Conflict of interest statement

AUTHOR DISCLOSURE STATEMENT The authors declare no conflicts of interest.

Figures

Fig. 1
Fig. 1
Comparison of changes before and after the intervention of lipid profile (total cholesterol, HDL-C, LDL-C, and triglycerides) and cardio-risk ratio (cholesterol/HDL-C) in FiberCreme and the control groups. *Significant difference at P<0.05. HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. Data are presented as mean±standard error.

References

    1. Calling S, Johansson SE, Wolff M, Sundquist J, Sundquist K. The ratio of total cholesterol to high density lipoprotein cholesterol and myocardial infarction in Women's Health in the Lund Area (WHILA): A 17-year follow-up cohort study. BMC Cardiovasc Disord. 2019;19:239. doi: 10.1186/s12872-019-1228-7. https://doi.org/10.1186/s12872-019-1228-7. - DOI - PMC - PubMed
    1. Caz V, Gil-Ramírez A, Largo C, Tabernero M, Santamaría M, Martín-Hernández R, et al. Modulation of cholesterol-related gene expression by dietary fiber fractions from edible mushrooms. J Agric Food Chem. 2015;63:7371–7380. doi: 10.1021/acs.jafc.5b02942. - DOI - PubMed
    1. Chen HL, Lu YH, Lin JJ, Ko LY. Effects of isomalto-oligosaccharides on bowel functions and indicators of nutritional status in constipated elderly men. J Am Coll Nutr. 2001;20:44–49. doi: 10.1080/07315724.2001.10719013. - DOI - PubMed
    1. Cronin P, Joyce SA, O'Toole PW, O'Connor EM. Dietary fibre modulates the gut microbiota. Nutrients. 2021;13:1655. doi: 10.3390/nu13051655. https://doi.org/10.3390/nu13051655. - DOI - PMC - PubMed
    1. Drissi F, Raoult D, Merhej V. Metabolic role of lactobacilli in weight modification in humans and animals. Microb Pathog. 2017;106:182–194. doi: 10.1016/j.micpath.2016.03.006. - DOI - PubMed

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