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Case Reports
. 2022 Jul;77(7-8):452-455.

[Monkeypox]

[Article in French]
G Absil  1 , L Sougne  2 , D Lahrichi  1 , P Collins  3 , C Meuris  4 , M Moutschen  4 , A F Nikkels  1 , C Orban  4
Affiliations
  • PMID: 35924502
Free article
Case Reports

[Monkeypox]

[Article in French]
G Absil et al. Rev Med Liege. 2022 Jul.
Free article

Abstract
in English, French

Monkeypox (MPX), is a rare endemic zoonotic disease of certain areas of Central and West Africa. Nevertheless, in recent years, several outbreaks have occurred outside the African continent. Monkeypox usually presents with a flu-like prodromal period (fever, headache, chills, sweating) associated or followed by the appearance of lymphadenopathy and a typical skin rash. Transmission is suspected to be direct or indirect via contact with saliva, respiratory droplets or skin lesions of infected animals or more rarely of humans. The gold standard for diagnosis is the detection of MPX virus (MPXV) by PCR on skin lesion fluid. The evolution is usually favourable in 2 to 5 weeks but severe complications and sequelae are possible. In the absence of a specific treatment, the management is essentially supportive: appropriate local care, rehydration, analgesia and management of eventual complications.

La variole du singe (monkeypox, MPX), ou orthopoxvirose simienne, est une zoonose rare et endémique de certains pays d’Afrique Centrale et de l’Ouest. Néanmoins, ces dernières années, plusieurs épidémies sont survenues en dehors du continent africain. La MPX se manifeste, habituellement, par un prodrome pseudogrippal (fièvre, céphalées, frissons, sudations), associé ou suivi par l’apparition d’une lymphadénopathie et d’un rash typique. La transmission serait directe ou indirecte, via contact avec la salive, les gouttelettes respiratoires ou les lésions cutanées d’animaux ou, plus rarement, d’humains contaminés. Le gold standard du diagnostic est la mise en évidence du virus monkeypox (MPXV) par «polymerase chain reaction» (PCR) sur lésion cutanée. L’évolution est habituellement favorable en 2 à 5 semaines, mais des complications et des séquelles sévères sont possibles. En l’absence d’un traitement spécifique, le traitement de soutien comporte: soins locaux adaptés, réhydratation, antalgie et prise en charge des éventuelles complications.

Keywords: Infection; Orthopoxvirus; Outbreak; Zoonotic disease; Monkeypox.

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