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Review
. 2022 Oct;71(10):801-810.
doi: 10.1007/s00101-022-01149-0. Epub 2022 Jun 23.

[Carbon monoxide intoxication-New aspects and current guideline-based recommendations]

[Article in German]
Affiliations
Review

[Carbon monoxide intoxication-New aspects and current guideline-based recommendations]

[Article in German]
A Fichtner et al. Anaesthesiologie. 2022 Oct.

Abstract

Carbon monoxide poisoning is a common and potentially life-threatening intoxication, showing an interindividual variety of unspecific symptoms as well as late neurological and other sequelae. Two new German guidelines (S2k guidelines diagnosis and treatment of carbon monoxide poisoning as well as S3 guidelines oxygen therapy in the acute care of adult patients) focus on current evidence-based information on diagnostics as well as therapeutic options with considerable uncertainty remaining. This review summarizes current information and presents a flow scheme for daily practical use.

Die Kohlenmonoxidintoxikation ist eine vergleichsweise häufige und potenziell lebensbedrohliche Intoxikation mit interindividuell unterschiedlicher und teilweise unspezifischer Symptomatik sowie verschiedenen – insbesondere neurologischen – Spätschäden. Zwei neue deutsche Leitlinien (S2k-Leitlinie Diagnostik und Therapie der Kohlenmonoxidvergiftung und AWMF-S3-Leitlinie Sauerstoff in der Akuttherapie beim Erwachsenen) behandeln die aktuelle Evidenz zur Diagnostik und insbesondere zur Therapie teilweise kontrovers. Diese Übersichtsarbeit fasst aktuelle Informationen zur Kohlenmonoxidintoxikation zusammen und stellt ein praktikables Handlungsschema auf.

Keywords: Flue gas; HBO; Neurological sequelae; Oxygen; Treatment.

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Literatur

    1. Azarov I, Wang L, Rose JJ, Xu Q, Huang XN, Belanger A, Wang Y, Guo L, Liu C, Ucer KB, McTiernan CF, O’Donnell CP, Shiva S, Tejero J, Kim-Shapiro DB, Gladwin MT (2016) Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning. Sci Transl Med 8(368):368ra173 - DOI
    1. Baran DA, Stelling K, McQueen D, Pearson M, Shah V (2020) Pediatric veno-veno extracorporeal membrane oxygenation rescue from carbon monoxide poisoning. Pediatr Emer Care 36(10):e592–e594
    1. Bickler MP, Rhodes LJ (2018) Accuracy of detection of carboxyhemoglobin and methemoglobin in human and bovine blood with an inexpensive, pocket-size infrared scanner. PLoS ONE 13(3):e193891 - DOI
    1. Birmingham CM, Hoffman RS (2011) Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials. Intensive Care Med. https://doi.org/10.1007/s00134-011-2195-3 - DOI - PubMed
    1. Bozeman WP, Myers RA, Barish RA (1997) Confirmation of the pulse oximetry gap in carbon monoxide poisoning. Ann Emerg Med 30(5):608–611 - DOI

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