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Editorial
. 2022 Nov;48(11):1642-1645.
doi: 10.1007/s00134-022-06834-7. Epub 2022 Aug 4.

Trauma-induced coagulopathy

Affiliations
Editorial

Trauma-induced coagulopathy

Derek J B Kleinveld et al. Intensive Care Med. 2022 Nov.
No abstract available

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Comment on

  • Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial.
    Baksaas-Aasen K, Gall LS, Stensballe J, Juffermans NP, Curry N, Maegele M, Brooks A, Rourke C, Gillespie S, Murphy J, Maroni R, Vulliamy P, Henriksen HH, Pedersen KH, Kolstadbraaten KM, Wirtz MR, Kleinveld DJB, Schäfer N, Chinna S, Davenport RA, Naess PA, Goslings JC, Eaglestone S, Stanworth S, Johansson PI, Gaarder C, Brohi K. Baksaas-Aasen K, et al. Intensive Care Med. 2021 Jan;47(1):49-59. doi: 10.1007/s00134-020-06266-1. Epub 2020 Oct 13. Intensive Care Med. 2021. PMID: 33048195 Free PMC article. Clinical Trial.

References

    1. Brohi K, Singh J, Heron M, Coats T (2003) Acute traumatic coagulopathy. J Trauma 54:1127–1130 - DOI
    1. Brohi K, Gruen RL, Holcomb JB (2019) Why are bleeding trauma patients still dying? Intensive Care Med 45:709–711 - DOI
    1. Brohi K, Cohen MJ, Ganter MT, Schultz MJ, Levi M, Mackersie RC, Pittet JF (2008) Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma 64:1211–1217 - PubMed
    1. Ostrowski SR, Henriksen HH, Stensballe J, Gybel-Brask M, Cardenas JC, Baer LA, Cotton BA, Holcomb JB, Wade CE, Johansson PI (2017) Sympathoadrenal activation and endotheliopathy are drivers of hypocoagulability and hyperfibrinolysis in trauma: a prospective observational study of 404 severely injured patients. J Trauma Acute Care Surg 82:293–301 - DOI
    1. Vulliamy P, Kornblith LZ, Kutcher ME, Cohen MJ, Brohi K, Neal MD (2021) Alterations in platelet behavior after major trauma: adaptive or maladaptive? Platelets 32:295–304 - DOI

MeSH terms

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