Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug 5;377(6606):588-589.
doi: 10.1126/science.add4834. Epub 2022 Aug 4.

Synchronizing neural rhythms

Affiliations

Synchronizing neural rhythms

Robert M G Reinhart. Science. .

Abstract

Personalized, noninvasive network-based neuromodulation aids impaired cognition.

PubMed Disclaimer

Figures

None
Multichannel high-definition frontotemporal (A) and orbitofrontal (B) neuromodulation protocols and electric-field models for high-definition transcranial alternating current stimulation (HD-tACS) are shown. The colored circles indicate electrodes. Network integrating reward and learning circuitry showing the reward feedback beta-gamma effect that is hypothesized to rise from the orbitofrontal cortex (OFC) and synchronize with the ventral striatum (VS) via beta-gamma rhythms is presented in (C). Amy, amygdala; dACC, dorsal anterior cingulate cortex; Hipp, hippocampus; SN, substantia nigra; Th, thalamus; VP, ventral pallidum; VTA, ventral tegmental area.

References

    1. Fries P, Neuron 88, 220 (2015). - PMC - PubMed
    1. Reinhart RMG, Nguyen JA, Nat. Neurosci. 22, 820 (2019). - PMC - PubMed
    1. Grover S, Nguyen JA, Reinhart RMG, Annu. Rev. Med. 72, 29 (2021). - PMC - PubMed
    1. Grover S, Nguyen JA, Viswanathan V, Reinhart RMG, Nat. Med. 27, 232 (2021). - PMC - PubMed
    1. Reinhart RMG, Proc. Natl. Acad. Sci. U.S.A. 114, 11542 (2017). - PMC - PubMed

Publication types