Mitochondria rescue cells from ischemic injury

Susana Cadenas^{1

2}

Affiliations

¹ Centro de Biología Molecular Severo Ochoa (CBMSO) (CSIC/UAM), Madrid, Spain.
² Instituto de Investigación Sanitaria del Hospital de la Princesa (IIS-IP), Madrid, Spain.

Comment

Susana Cadenas. Science. 2022.

. 2022 Aug 5;377(6606):579-580.

doi: 10.1126/science.add4629. Epub 2022 Aug 4.

Susana Cadenas^{1

2}

¹ Centro de Biología Molecular Severo Ochoa (CBMSO) (CSIC/UAM), Madrid, Spain.
² Instituto de Investigación Sanitaria del Hospital de la Princesa (IIS-IP), Madrid, Spain.

Abstract

Activation of a G protein-coupled receptor prevents cardiomyocyte death during ischemia.

Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.
Wyant GA, Yu W, Doulamis IP, Nomoto RS, Saeed MY, Duignan T, McCully JD, Kaelin WG Jr. Wyant GA, et al. Science. 2022 Aug 5;377(6606):621-629. doi: 10.1126/science.abm1638. Epub 2022 Aug 4. Science. 2022. PMID: 35926043 Free PMC article.