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Comment
. 2022 Aug 5;377(6606):575-576.
doi: 10.1126/science.add7145. Epub 2022 Aug 4.

Twice the tolerance

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Comment

Twice the tolerance

Meera K Shenoy et al. Science. .

Abstract

A gut microbiota-derived antigen elicits distinct subsets of regulatory T cells to suppress inflammation in mice.

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  • A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes.
    Bousbaine D, Fisch LI, London M, Bhagchandani P, Rezende de Castro TB, Mimee M, Olesen S, Reis BS, VanInsberghe D, Bortolatto J, Poyet M, Cheloha RW, Sidney J, Ling J, Gupta A, Lu TK, Sette A, Alm EJ, Moon JJ, Victora GD, Mucida D, Ploegh HL, Bilate AM. Bousbaine D, et al. Science. 2022 Aug 5;377(6606):660-666. doi: 10.1126/science.abg5645. Epub 2022 Aug 4. Science. 2022. PMID: 35926021 Free PMC article.

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