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. 2022 Aug 1;117(8):1197-1220.
doi: 10.14309/ajg.0000000000001874. Epub 2022 Jun 3.

ACG Clinical Guideline: Gastroparesis

Michael Camilleri  1 , Braden Kuo  2 , Linda Nguyen  3 , Vida M Vaughn  4 , Jessica Petrey  4 , Katarina Greer  5 , Rena Yadlapati  6 , Thomas L Abell  4
Affiliations

ACG Clinical Guideline: Gastroparesis

Michael Camilleri et al. Am J Gastroenterol. .

Abstract

Gastroparesis is characterized by symptoms suggesting retention of food in the stomach with objective evidence of delayed gastric emptying in the absence of mechanical obstruction in the gastric outflow. This condition is increasingly encountered in clinical practice. These guidelines summarize perspectives on the risk factors, diagnosis, and management of gastroparesis in adults (including dietary, pharmacological, device, and interventions directed at the pylorus), and they represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation process. When the evidence was not appropriate for Grading of Recommendations, Assessment, Development, and Evaluation, we used expert consensus to develop key concept statements. These guidelines should be considered as preferred but are not the only approaches to these conditions.

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Conflict of interest statement

Potential conflicts of interest:

MC: Single-center research studies: Allergan, Takeda, and Vanda; Consulting with compensation to his employer: Takeda, Alpha Sigma Wasserman

TA: Investigator: Censa, Clndome, Vanda, Allergan, Neurogastrix; Consultant: Censa, Nuvaira, Takeda, Medtronic; Speaker: Takeda, Medtronic; Reviewer: UpToDate; Writer: Med Study; Editorial: Neuromodulation, Wikistim; ADEPT-GI: IP for autonomic/enteric diagnosis and therapies

BK: Clinical trials with Takeda, Vanda, Alpha Sigma Wasserman, GSK; Consulting with Takeda, Cindome, Neurogastrix; Speaking for Medtronic

LN: Investigator: Allergan, Vanda; Consultant: Abbvie, Ironwood, Alnylam, Eli Lilly, Gemelli, Neurogastrx, Pendulum, Phathom, RosVivo, Salix, Takeda. Scientific Advisory Board: Gemelli, RosVivo

VMV: Nothing to disclose

JP: Nothing to disclose

KG: Nothing to disclose

RY: Consultant through Institutional Agreement: Medtronic, Ironwood Pharmaceuticals, Diversatek, StatLinkMD; Research support: Ironwood Pharmaceuticals; Advisory Board: Phathom Pharmaceuticals; RJS Mediagnostix

Figures

Figure 1.
Figure 1.
This algorithm updates the algorithm from the 2013 ACG guideline on gastroparesis (1).
See this image and copyright information in PMC

References

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    1. Friedenberg FK, Palit A, Parkman HP, Hanlon A, Nelson DB. Botulinum toxin A for the treatment of delayed gastric emptying. Am J Gastroenterol. 2008;103:416–23 - PubMed

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