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. 2022 Jan-Dec:21:23259582221117009.
doi: 10.1177/23259582221117009.

Outcomes of HIV Positive Children and Adolescents Initiated on Antiretroviral Treatment in Nigeria (2007-2016)

Onyekachi Anukam  1 , Natalia Blanco  2 , Jibreel Jumare  2 , Julia Lo  2 , Ezra Babatunde  1 , Solomon Odafe  3 , Dennis Onotu  3 , Uzoma Ene  3 , Johnson Fagbamigbe  3 , Deborah Carpenter  4 , Emilia D Rivadeneira  4 , Austin I Omoigberale  5   6 , Manhattan Charurat  2 , Mahesh Swaminathan  3 , Kristen A Stafford  2
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Outcomes of HIV Positive Children and Adolescents Initiated on Antiretroviral Treatment in Nigeria (2007-2016)

Onyekachi Anukam et al. J Int Assoc Provid AIDS Care. 2022 Jan-Dec.

Abstract

Background: This manuscript aimed to examine treatment outcomes of HIV-positive children and adolescents. Methods: We retrospectively analyzed data of a sample of patients aged 0-19 years who initiated ART (October 2007-September 2016) in participating sites in 30 states and the Federal Capital Territory in Nigeria. Results: Among 4006 patients alive at the end of the follow up period, 138 (3.4%) were LTFU. Adolescents had a significantly higher risk of being LTFU than children aged 3-5 years (HR 2.47 [95% CI 1.40-4.34]). Patients with advanced disease had a significantly higher risk of being LTFU (Stage IV HR, 3.66 [95% CI: 2.00-6.68]). On average, optimal ART refill adherence was met by 67.3% of patients. Conclusion: Our findings suggest that focusing on preventing and managing advanced disease and interventions supporting adolescents when transferring to adult care is warranted.

Keywords: HIV; adolescents; antiretroviral therapy; children.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Mean estimates of CD4 + cell counts by age group across time among participants.
See this image and copyright information in PMC

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