Belly Fat Weakens Immune Fitness
- PMID: 35929132
- DOI: 10.1158/2159-8290.CD-22-0611
Belly Fat Weakens Immune Fitness
Erratum in
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Correction: Belly Fat Weakens Immune Fitness.Cancer Discov. 2022 Nov 2;12(11):2710. doi: 10.1158/2159-8290.CD-22-1073. Cancer Discov. 2022. PMID: 36321310 No abstract available.
Abstract
Much work has been done to reduce cancer immunosuppression through inhibiting soluble proteins, surface molecules, and suppressive cells. This article shows an important role for the lipid lysophosphatidic acid, whose suppression shows promise as a novel cancer immunotherapeutic, demonstrated in ovarian cancer. See related article by Chae et al., 1904 (5).
©2022 American Association for Cancer Research.
Comment on
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Tumor-Derived Lysophosphatidic Acid Blunts Protective Type I Interferon Responses in Ovarian Cancer.Cancer Discov. 2022 Aug 5;12(8):1904-1921. doi: 10.1158/2159-8290.CD-21-1181. Cancer Discov. 2022. PMID: 35552618 Free PMC article.
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