T cell development made EZ
- PMID: 35931025
- DOI: 10.1016/j.stem.2022.07.003
T cell development made EZ
Abstract
In this issue of Cell Stem Cell, Jing et al. inhibit EZH1 expression in a system that supports mature T cell development from iPSCs in vitro. The authors efficiently generate T cells that are highly functional against tumors.
Published by Elsevier Inc.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity.Cell Stem Cell. 2022 Aug 4;29(8):1181-1196.e6. doi: 10.1016/j.stem.2022.06.014. Cell Stem Cell. 2022. PMID: 35931029 Free PMC article.
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