ZBP1 induces immunopathology caused by loss of ADAR1-mediated RNA editing

Affiliations

Kirsty Minton. Nat Rev Immunol. 2022 Sep.

. 2022 Sep;22(9):531.

doi: 10.1038/s41577-022-00772-7.

No abstract available

Republished from

ADAR1 inhibits ZBP1 activation by endogenous Z-RNA.
Minton K. Minton K. Nat Rev Genet. 2022 Oct;23(10):581. doi: 10.1038/s41576-022-00525-1. Nat Rev Genet. 2022. PMID: 35922480 No abstract available.

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1. de Reuver, R. et al. ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation. Nature https://doi.org/10.1038/s41586-022-04974-w (2022) - DOI - PubMed
1. Jiao, H. et al. ADAR1 averts fatal type I interferon induction by ZBP1. Nature https://doi.org/10.1038/s41586-022-04878-9 (2022) - DOI - PubMed - PMC

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