doi: 10.1016/0006-291x(87)91367-2.
Phosphatidylserine vesicles increase rat brain synaptosomal adenylate cyclase activity
- PMID: 3593357
- DOI: 10.1016/0006-291x(87)91367-2
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Phosphatidylserine vesicles increase rat brain synaptosomal adenylate cyclase activity
Biochem Biophys Res Commun.
.
Abstract
Phosphatidylserine vesicles incubated in hypotonic conditions with rat brain synaptosomes increased basal adenylate cyclase activity but did not modify the response of the enzyme to norepinephrine. Moreover, phosphatidylserine antagonized the stimulation of adenylate cyclase activity by NaF. We suggest that in present experimental conditions the effect of phosphatidylserine vesicles is at the level of the GS regulatory protein of adenylate cyclase.
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