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. 2022 Nov;85(5):573-607.
doi: 10.1016/j.jinf.2022.07.027. Epub 2022 Aug 4.

Clinical and virological characteristics of SARS-CoV-2 Omicron BA.2.2 variant outbreaks during April to May, 2022, Shanghai, China

Yuanyun Ao  1 , Jingjing Li  2 , Zhongqiu Wei  2 , Zhonglin Wang  2 , He Tian  2 , Yue Qiu  2 , Xiaomin Fu  2 , Wenjie Ma  2 , Liting Li  2 , Mei Zeng  3 , Jin Xu  4
Affiliations

Clinical and virological characteristics of SARS-CoV-2 Omicron BA.2.2 variant outbreaks during April to May, 2022, Shanghai, China

Yuanyun Ao et al. J Infect. 2022 Nov.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest All the authors declared no conflicts of interest.

Figures

Fig 1
Fig. 1
Viral shedding and genetic characteristics of SARS-CoV-2 Omicron BA.2.2 variants, Shanghai, China. (A) The temporal profile of serial viral RNA shedding in nasal swab from children and adults. (B, C) Comparison of peak viral RNA load and duration of viral RNA shedding between children and adults. Each dot represented a case; box tops and bottoms indicated interquartile range, while horizontal lines denoted medians. A lower Ct value (cycle threshold) indicated a higher viral load. P value were calculated by the Kruskal-Wallis test. *P < 0.05, ****P <  0.0001; ns, not significant. (D, E) Comparison of peak viral RNA load and duration of viral RNA shedding between different age group of children. (F) Maximum likelihood phylogenetic tree of genomic sequences from BA.2.2 strains. A total of 251 sequences were included for both analyses. Each strain was represented by a circle and colored based on their identified locations in China, while those identified from other counties were not indicated. The new emergent BA.2.2 cluster was indicated in pink shading. (G) Schematic illustration of proteins and their interesting mutations in Shanghai BA.2.2 strains. The Wuhan-Hu-1/2019 (MN908947) was used as the compared reference sequence. The common mutations in all BA.2.2 strains were indicated by cyan shading; the unique mutations in Shanghai BA.2.2 strains were highlighted by pink shading; the unique mutations with a high occur frequency in Shanghai BA.2.2 strains were indicated by black strangle.
See this image and copyright information in PMC

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