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. 2022 Jul 27;37(1):440.
doi: 10.4102/sajid.v37i1.440. eCollection 2022.

Descriptive analysis of infections due to New Delhi metallo-β-lactamase-producing Enterobacterales in children at Red Cross War Memorial Children's Hospital

Leonore Greybe  1   2 , James J C Nuttall  1   2 , Adrian J Brink  3   4 , Hafsah D Tootla  3   4
Affiliations

Descriptive analysis of infections due to New Delhi metallo-β-lactamase-producing Enterobacterales in children at Red Cross War Memorial Children's Hospital

Leonore Greybe et al. S Afr J Infect Dis. .

Abstract

The increased incidence and absence of antibiotic treatment options for New Delhi metallo-β-lactamase (NDM)-producing carbapenem-resistant Enterobacterales (CRE) infection are concerning. Recent reports have highlighted NDM-producing Serratia marcescens, as a specific concern, as it is an organism which is intrinsically resistant to colistin. In this study, a descriptive analysis of NDM-producing CRE infections was performed at the Red Cross War Memorial Children's Hospital.

Keywords: Enterobacterales; New Delhi metallo-β-lactamase; Serratia marcescens; antibiotic resistance; carbapenem resistance; carbapenemases; paediatrics.

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Conflict of interest statement

The authors have no financial or personal relationships that may have inappropriately influenced them in writing this article.

Figures

FIGURE 1
FIGURE 1
Graphic representation of (a) risk factors for infection with NDM-producing Enterobacterales, (b) the number of NDM-producing Enterobacterales identified during the study period by organism, (c) antibiogram of NDM-producing Enterobacterales (number of susceptible isolates to currently available antibiotics), and (d) outcome stratified by organism, antibiotic susceptibility and antibiotic treatment received.
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