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. 2022 Jul 22:2022:2452282.
doi: 10.1155/2022/2452282. eCollection 2022.

Application of Multimodal Magnetic Resonance Imaging in Green Channel of Acute and Hyperacute Ischemic Stroke

Jianguo Zhou  1 , Guifen Li  2 , Yun Meng  1 , Dayong Fu  1 , Mingcong Lu  1 , Zhi Tang  3
Affiliations

Application of Multimodal Magnetic Resonance Imaging in Green Channel of Acute and Hyperacute Ischemic Stroke

Jianguo Zhou et al. Contrast Media Mol Imaging. .

Abstract

The purpose of this study was to observe the effects of multimodal magnetic resonance imaging (MRI) in the green channel of acute and hyperacute ischemic strokes, in order to better guide clinical treatment. The clinical data of 126 patients with acute and hyperacute ischemic stroke who received interventional treatment in the emergency green channel was collected retrospectively. The patients who received multimodal computed tomography (CT) were included in the CT group. Patients who underwent multimodal MRI examinations were included in the MRI group, and the door-to-needle time (DNT), neurological function, and prognosis of the two groups were compared. The result turned out that among the 126 patients included, 40 patients underwent CT examination (CT group) and 86 patients underwent MRI examination (MRI group). A comparison of general data between the CT group and the MRI group showed P > 0.05. The MRI group's DNT time (61.23 ± 9.32) min was shorter than that of the CT group (87.22 ± 14.26) min, P < 0.05. Through comparison, the P values of mRS scores and NIHSS scores in both groups were greater than 0.05. After treatment, the mRS score and NIHSS score of the MRI group was lower, with P < 0.05. According to the results of this study, it can be concluded that emergency multimodal MRI could shorten the DNT time of patients with acute and hyperacute ischemic stroke, reduce the degree of neurological impairment, and improve the prognosis.

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Conflict of interest statement

The authors declare that there are no conflicts of interest regarding the publication of this paper.

Figures

Figure 1
Figure 1
The detailed steps of this study. Note: DNT = door-to-needle time, mRS = modified Rankin Scale, and NIHSS = NIH Stroke Scale.
Figure 2
Figure 2
MRI image of a patient. Note: the patient was a 49-year-old man with impaired right limb movement and slurred speech for 2 hours. In (a) and (b), DWI shows patchy higher signal intensity in the left frontal lobe, insula, and lateral ventricular asides (hyperacute ischemic stroke). In (c) and (d), ADC suggests patchy low signal in the voiceover area of the left frontal lobe, insula, and lateral ventricle. In (e)–(h), SWAN indicates increased distribution of draining and decreased signal of left frontal temporal lobe and insular pia meningeal. In addition, the distribution of medullary veins in the voiceover area of the lateral ventricle increased and signal decreased (positive PVS). In (I) and (j), 3D-TOF MRA suggests occlusion of the M1 segment of the left middle cerebral artery.
Figure 3
Figure 3
DNT time. Note: there were 40 cases in CT Group and 86 cases in MRI Group. ∗represents data comparison, P < 0.05.
Figure 4
Figure 4
mRS scores. Note: there were 40 cases in CT Group and 86 cases in the MRI Group. ∗represents data comparison, P < 0.05.
Figure 5
Figure 5
NIHSS scores. Note: there were 40 cases in CT Group and 86 cases in MRI Group. ∗represents data comparison, P < 0.05.
See this image and copyright information in PMC

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