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Review
. 2022 Jul 22:10:907589.
doi: 10.3389/fbioe.2022.907589. eCollection 2022.

Role of chitosan in titanium coatings. trends and new generations of coatings

Nansi López-Valverde  1 , Javier Aragoneses  1 , Antonio López-Valverde  2 , Cinthia Rodríguez  3 , Bruno Macedo de Sousa  4 , Juan Manuel Aragoneses  5
Affiliations
Review

Role of chitosan in titanium coatings. trends and new generations of coatings

Nansi López-Valverde et al. Front Bioeng Biotechnol. .

Abstract

Survival studies of dental implants currently reach high figures. However, considering that the recipients are middle-aged individuals with associated pathologies, research is focused on achieving bioactive surfaces that ensure osseointegration. Chitosan is a biocompatible, degradable polysaccharide with antimicrobial and anti-inflammatory properties, capable of inducing increased growth and fixation of osteoblasts around chitosan-coated titanium. Certain chemical modifications to its structure have been shown to enhance its antibacterial activity and osteoinductive properties and it is generally believed that chitosan-coated dental implants may have enhanced osseointegration capabilities and are likely to become a commercial option in the future. Our review provided an overview of the current concepts and theories of osseointegration and current titanium dental implant surfaces and coatings, with a special focus on the in vivo investigation of chitosan-coated implants and a current perspective on the future of titanium dental implant coatings.

Keywords: bioactive surfaces3; chitosan coating4; future direction5; osteointegration2; titanium dental implants1.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Osseointegration and failure.
FIGURE 2
FIGURE 2
Engraved and machined surface of Ti implants.
FIGURE 3
FIGURE 3
Chitin deacetylation process.
FIGURE 4
FIGURE 4
Modified Vakili and Zhang coating scheme for the immersion procedure.
See this image and copyright information in PMC

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