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Case Reports
. 2022 Aug 3;10(8):e6165.
doi: 10.1002/ccr3.6165. eCollection 2022 Aug.

COVID-19-associated mucormycosis involving the maxilla

Mahboube Hasheminasab  1 , Mojtaba Salehi Karizmeh  1 , Reza Sharifi  1 , Majid Beshkar  1 , Narges Matloubi  1 , Amir Ali Asadi  1 , Elham Nazar  2
Affiliations
Case Reports

COVID-19-associated mucormycosis involving the maxilla

Mahboube Hasheminasab et al. Clin Case Rep. .

Abstract

It is important to increase the awareness and knowledge of head and neck surgeons about the recent surge of craniofacial mucormycosis in COVID-19 patients because early diagnosis and appropriate treatment are essential to improve the outcomes. Here, we describe clinical features, treatment protocols, and outcomes of treatment in eight patients with COVID-19-associated mucormycosis in the maxilla. Consistent with the findings of previous studies, our experience in the management of these eight patients shows that early administration of amphotericin B and prompt aggressive surgery are essential for optimal control of the disease.

Keywords: COVID‐19; Mucormycosis; maxilla; pandemic.

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Conflict of interest statement

The authors have none.

Figures

FIGURE 1
FIGURE 1
Exposure of necrotic maxillary bone in a patient with COVID‐19‐associated mucormycosis
FIGURE 2
FIGURE 2
Axial CT scan of the maxilla in a patient with COVID‐19‐associated mucormycosis. Bone destruction is evident in the left hemi‐maxilla, involving both the alveolar bone and the basal bone
FIGURE 3
FIGURE 3
Section shows extensive necrosis with broad aseptate ribbon‐like fungal hyphae (H&E staining). Black arrow: fungal hyphae. (x400)
FIGURE 4
FIGURE 4
Section shows broad aseptate ribbon‐like hyphae (Periodic acid–Schiff [PAS] staining, x400).
See this image and copyright information in PMC

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