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Review
. 2022 Jun 8;36(2):75-82.
doi: 10.1055/s-0042-1749095. eCollection 2022 May.

Novel Technologies in Chronic Wound Care

Yehiel Hayun  1   2 , Dafna Shilo Yaacobi  1   2 , Tal Shachar  3 , Moti Harats  2   4 , Andrew E Grush  5   6 , Asaf Olshinka  2   7
Affiliations
Review

Novel Technologies in Chronic Wound Care

Yehiel Hayun et al. Semin Plast Surg. .

Abstract

In Israel, 20% of wounds do not progress to full healing under treatment with conservative technologies of which 1 to 2% are eventually defined as chronic wounds. Chronic wounds are a complex health burden for patients and pose considerable therapeutic and budgetary burden on health systems. The causes of chronic wounds include systemic and local factors. Initial treatment involves the usual therapeutic means, but as healing does not progress, more advanced therapeutic technologies are used. Undoubtedly, advanced means, such as negative pressure systems, and advanced technologies, such as oxygen systems and micrografts, have vastly improved the treatment of chronic wounds. Our service specializes in treating ulcers and difficult-to-heal wounds while providing a multiprofessional medical response. Herein, we present our experience and protocols in treating chronic wounds using a variety of advanced dressings and technologies.

Keywords: advanced dressings; advanced technologies; chronic wounds; wound care.

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Conflict of interest statement

Conflicts of Interest None declared.

Figures

Fig. 1
Fig. 1
A standardized sample preparation system for the automated mechanical disaggregation of the cell population.
Fig. 2
Fig. 2
Rigenera technology: the injection of micrograft to a patient with a neck burn who was not scheduled for surgery due to a complex medical condition. ( A ) Before treatment, ( B ) 1 month following treatment.
Fig. 3
Fig. 3
E-QURE BST device: a computerized controlled single-channel bioelectrical stimulator.
Fig. 4
Fig. 4
E-QURE BST technology: ( A ) a 6-month chronic injury, ( B ) 18 months post biopsy without any conventional dressing.
Fig. 5
Fig. 5
NATROX technology: a battery-operated device that delivers continuous pure humidified oxygen to the wound bed through water electrolysis.
Fig. 6
Fig. 6
NATROX technology: ( A ) a scalp wound following tissue removal, without the ability to use flaps, ( B ) 3 months following treatment.
Fig. 7
Fig. 7
ActiGraft technology: the fibrin matrix derived from the patient's own blood.
Fig. 8
Fig. 8
ActiGraft: ( A and B ) a traumatic wound with exposed bone, ( C ) 1 month after four rounds of ActiGraft therapy.
Fig. 9
Fig. 9
Matriderm technology: a collagen-elastin scaffold.
Fig. 10
Fig. 10
Matriderm technology: ( A ) a traumatic necrotic orthopedic wound, ( B ) which underwent debridement, ( C ) vacuum-assisted closure, and then closure with Matriderm and ( D ) development of well-granulated wound. ( E ) Wound coverage with split thickness skin graft. ( F ) Successful resolution of the wound.
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