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Case Reports
. 2022 Jul 1:26:98-100.
doi: 10.1016/j.jdcr.2022.06.017. eCollection 2022 Aug.

Successful treatment of ivermectin refractory demodicosis with isotretinoin and permethrin cream

Anon Paichitrojjana  1 , Anand Paichitrojjana  2
Affiliations
Case Reports

Successful treatment of ivermectin refractory demodicosis with isotretinoin and permethrin cream

Anon Paichitrojjana et al. JAAD Case Rep. .
No abstract available

Keywords: Demodex mite; SSSB, standardized skin surface biopsy; demodicosis; isotretinoin; ivermectin; permethrin.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Dry, scaly, erythematous patches and telangiectasia with a stinging and burning sensation on both cheeks.
Fig 2
Fig 2
Complete resolution of all clinical symptoms after 8 weeks of treatment with isotretinoin and permethrin cream.
See this image and copyright information in PMC

References

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    1. Paichitrojjana A. Demodex: the worst enemies are the ones that used to be friends. Dermatol Rep. 2022 doi: 10.4081/dr.2022.9339. - DOI - PMC - PubMed
    1. Salem D.A., El-Shazly A., Nabih N., El-Bayoumy Y., Saleh S. Evaluation of the efficacy of oral ivermectin in comparison with ivermectin– metronidazole combined therapy in the treatment of ocular and skin lesions of Demodex folliculorum. Int J Infect Dis. 2013;17(5):e343–e347. doi: 10.1016/j.ijid.2012.11.022. - DOI - PubMed
    1. Forton F., De Maertelaer V. Erythematotelangiectatic rosacea may be associated with a subclinical stage of demodicosis: a case-control study. Br J Dermatol. 2019;181(4):818–825. doi: 10.1111/bjd.17817. - DOI - PubMed
    1. Baraka O.Z., Mahmoud B.M., Marschke C.K., et al. Ivermectin distribution in the plasma and tissues of patients infected with Onchocerca volvulus. Eur J Clin Pharmacol. 1996;50:407–410. doi: 10.1007/s002280050131. - DOI - PubMed

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