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. 2022 Sep 6;328(9):883-884.
doi: 10.1001/jama.2022.12407.

Serum Cystatin C for Estimation of GFR

Michael G Shlipak  1 , Lesley A Inker  2 , Josef Coresh  3
Affiliations

Serum Cystatin C for Estimation of GFR

Michael G Shlipak et al. JAMA. .

Erratum in

  • Error in Table.
    [No authors listed] [No authors listed] JAMA. 2022 Dec 13;328(22):2274. doi: 10.1001/jama.2022.21078. JAMA. 2022. PMID: 36511940 Free PMC article. No abstract available.
No abstract available

Plain language summary

An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for persistent hyperkalemia. The patient was frail and sedentary, with a BMI of 37. His estimated glomerular filtration rate calculated using creatinine was 64 mL/min/1.73 m2. How would you interpret these results?

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Conflict of interest statement

Conflict of Interest Disclosures

Dr Shlipak reported receiving grants from the National Institutes of Health/National Heart, Lung, and Blood Institute/National Institute on Aging/National Institute of Diabetes and Digestive and Kidney Diseases during the conduct of the study and grants from Bayer Pharmaceuticals and personal fees from Cricket Health, Intercept Pharmaceuticals, Bayer Pharmaceuticals, AstraZeneca, and Boehringer Ingelheim outside the submitted work. Dr Inker reported receiving grants from the National Institutes of Health and providing consultancy to Health Logics outside the submitted work. Dr Coresh reported consulting for Health.io during the conduct of the study and consulting for SomaLogic and receiving grants from the National Institutes of Health and National Kidney Foundation outside the submitted work.

References

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    1. Inker LA, Eneanya ND, Coresh J, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med. 2021;385(19):1737–1749. - PMC - PubMed
    1. Delgado C, Baweja M, Crews DC, et al. A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease. Am J Kidney Dis. 2022;79(2):268–288 e261. - PubMed
    1. Gutierrez OM, Sang Y, Grams ME, et al. Association of Estimated GFR Calculated Using Race-Free Equations With Kidney Failure and Mortality by Black vs Non-Black Race. JAMA. 2022. - PMC - PubMed
    1. Levey AS, Inker LA, Coresh J. GFR estimation: from physiology to public health. Am J Kidney Dis. 2014;63(5):820–834. - PMC - PubMed