Changing Epidemiology of Cirrhosis and Hepatic Encephalopathy

doi:10.1016/j.cgh.2022.04.036

Review

. 2022 Aug;20(8S):S1-S8.

doi: 10.1016/j.cgh.2022.04.036.

Changing Epidemiology of Cirrhosis and Hepatic Encephalopathy

Jeremy Louissaint¹, Sasha Deutsch-Link², Elliot B Tapper³

Affiliations

¹ Center for Liver Disease and Transplantation, Columbia University, New York, New York.
² Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina.
³ Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan. Electronic address: etapper@umich.edu.

PMID: 35940729
PMCID: PMC9531320
DOI: 10.1016/j.cgh.2022.04.036

Review

Changing Epidemiology of Cirrhosis and Hepatic Encephalopathy

Jeremy Louissaint et al. Clin Gastroenterol Hepatol. 2022 Aug.

. 2022 Aug;20(8S):S1-S8.

doi: 10.1016/j.cgh.2022.04.036.

Authors

Jeremy Louissaint¹, Sasha Deutsch-Link², Elliot B Tapper³

Affiliations

¹ Center for Liver Disease and Transplantation, Columbia University, New York, New York.
² Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina.
³ Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan. Electronic address: etapper@umich.edu.

PMID: 35940729
PMCID: PMC9531320
DOI: 10.1016/j.cgh.2022.04.036

No abstract available

Keywords: Cognitive Dysfunction; Encephalopathy; Liver Disease.

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Figures

**Figure 1.**
Contributors to the epidemiology of HE and their impact. Many comorbidities and lifestyle behaviors contribute to the development of HE. The impact of HE is broad and has consequences for the individual, their household and community, and the health care system. CKD, Chronic kidney disease; NASH, nonalcoholic steatohepatitis.

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References

1. D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217–231. - PubMed
1. Tapper EB, Aberasturi D, Zhao Z, et al. Outcomes after hepatic encephalopathy in population-based cohorts of patients with cirrhosis. Aliment Pharmacol Ther 2020;51:1397–1405. - PMC - PubMed
1. Tapper EB, Henderson JB, Parikh ND, et al. Incidence of and risk factors for hepatic encephalopathy in a population-based cohort of Americans with cirrhosis. Hepatol Commun 2019;3:1510–1519. - PMC - PubMed
1. Sanyal AJ, Van Natta ML, Clark J, et al. NASH Clinical Research Network (CRN). Prospective study of outcomes in adults with nonalcoholic fatty liver disease. N Engl J Med 2021;385:1559–1569. - PMC - PubMed
1. Vilstrup H, Amodio P, Bajaj J, et al. Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology 2014;60:715–735. - PubMed

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[1] D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217–231. - PubMed

[2] D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217–231. - PubMed

[3] Tapper EB, Aberasturi D, Zhao Z, et al. Outcomes after hepatic encephalopathy in population-based cohorts of patients with cirrhosis. Aliment Pharmacol Ther 2020;51:1397–1405. - PMC - PubMed

[4] Tapper EB, Aberasturi D, Zhao Z, et al. Outcomes after hepatic encephalopathy in population-based cohorts of patients with cirrhosis. Aliment Pharmacol Ther 2020;51:1397–1405. - PMC - PubMed

[5] Tapper EB, Henderson JB, Parikh ND, et al. Incidence of and risk factors for hepatic encephalopathy in a population-based cohort of Americans with cirrhosis. Hepatol Commun 2019;3:1510–1519. - PMC - PubMed

[6] Tapper EB, Henderson JB, Parikh ND, et al. Incidence of and risk factors for hepatic encephalopathy in a population-based cohort of Americans with cirrhosis. Hepatol Commun 2019;3:1510–1519. - PMC - PubMed

[7] Sanyal AJ, Van Natta ML, Clark J, et al. NASH Clinical Research Network (CRN). Prospective study of outcomes in adults with nonalcoholic fatty liver disease. N Engl J Med 2021;385:1559–1569. - PMC - PubMed

[8] Sanyal AJ, Van Natta ML, Clark J, et al. NASH Clinical Research Network (CRN). Prospective study of outcomes in adults with nonalcoholic fatty liver disease. N Engl J Med 2021;385:1559–1569. - PMC - PubMed

[9] Vilstrup H, Amodio P, Bajaj J, et al. Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology 2014;60:715–735. - PubMed

[10] Vilstrup H, Amodio P, Bajaj J, et al. Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology 2014;60:715–735. - PubMed

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Changing Epidemiology of Cirrhosis and Hepatic Encephalopathy

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Changing Epidemiology of Cirrhosis and Hepatic Encephalopathy

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