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Review
. 2022 Nov 1;37(6):0.
doi: 10.1152/physiol.00016.2022. Epub 2022 Aug 9.

COVID-19 and Inborn Errors of Immunity

Ottavia M Delmonte  1 , Riccardo Castagnoli  1   2   3 , Luigi D Notarangelo  1
Affiliations
Review

COVID-19 and Inborn Errors of Immunity

Ottavia M Delmonte et al. Physiology (Bethesda). .

Abstract

Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune host defense and immunoregulation. Considering the predisposition to develop severe and chronic infections, it is crucial to understand the clinical evolution of COVID-19 in IEI patients. This review analyzes clinical outcomes following SARS-CoV-2 infection, as well as response to COVID-19 vaccines in patients with IEI.

Keywords: COVID-19; COVID-19 vaccine; SARS-COV-2; inborn errors of immunity; primary immune deficiency.

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Conflict of interest statement

No conflicts of interest, financial or otherwise, are declared by the authors.

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