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Case Reports
. 2024 Jan 1;18(1):18-23.
doi: 10.1097/ICB.0000000000001303.

MANAGEMENT OF RETINAL DETACHMENT ASSOCIATED WITH MORNING GLORY SYNDROME USING THE HUMAN AMNIOTIC MEMBRANE

Tomaso Caporossi  1   2 , Silvia Ferrara  1   2 , Alfonso Savastano  1 , Gloria Gambini  1 , Umberto De Vico  1 , Maria Cristina Savastano  1   2 , Stanislao Rizzo  1   2   3
Affiliations
Case Reports

MANAGEMENT OF RETINAL DETACHMENT ASSOCIATED WITH MORNING GLORY SYNDROME USING THE HUMAN AMNIOTIC MEMBRANE

Tomaso Caporossi et al. Retin Cases Brief Rep. .

Abstract

Purpose: This case report describes an innovative procedure for addressing retinal detachment in patients with morning glory syndrome.

Methods: An 18-year-old woman with unilateral morning glory syndrome complicated by macula-off retinal detachment without any visible peripheral retinal breaks underwent three corrective surgeries. In the first surgery, a 25-gauge pars plana vitrectomy with a 3-mm human amniotic membrane patch positioned on the optic disc and gas endotamponade was performed. When the gas reabsorbed, inferior retinal detachment recurred, and a second vitrectomy with silicone oil endotamponade was conducted. At three months, the retina was still attached under the silicone oil, so the oil was removed. At the second follow-up, retinal detachment had recurred, and a third vitrectomy with a larger amniotic patch and silicone oil endotamponade was performed.

Results: Three months following the last surgery, the subretinal fluid had totally reabsorbed, and the retina was completely attached. The best-corrected visual acuity was 20/100.

Conclusion: To the best of our knowledge, the first description of a human amniotic patch associated with vitrectomy in morning glory syndrome complicated with retinal detachment is described. Using human amniotic membranes, positioned onto the optic nerve, and silicone oil endotamponade could be useful for morning glory syndrome complicated by retinal detachment.

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References

    1. Kindler P. Morning glory syndrome: unusual congenital optic disk anomaly. Am J Ophthalmol 1970;69:376–384.
    1. Ceynowa DJ, Wickstrom R, Olsson M, et al. Morning glory disc anomaly in childhood—a population-based study. Acta Ophthalmol 2015;93:626–634.
    1. Sakamoto M, Kuniyoshi K, Hayashi S, et al. Total retinal detachment and contractile movement of the disc in eyes with morning glory syndrome. Am J Ophthalmol Case Rep 2020;20:100964.
    1. Miller NR, Newman NJ, eds. Anomalies of the optic disc. In: The Essentials: Walsh & Hoyt's Clinical Neuro-Ophthalmology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 1999:117–123.
    1. Dutton GN. Congenital disorders of the optic nerve: excavations and hypoplasia. Eye (Lond) 2004;18:1038–1048.

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