Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978;7(5):557-66.
doi: 10.3109/08820137809025484.

Effect of delta9-tetrahydrocannabinol on in vitro sensitization of mouse splenic lymphocytes

S S Lefkowitz, K Klager

Effect of delta9-tetrahydrocannabinol on in vitro sensitization of mouse splenic lymphocytes

S S Lefkowitz et al. Immunol Commun. 1978.

Abstract

The effects of delta9-tetrahydrocannabinol (delta9-THC) on the immune response of murine cells sensitized in vitro was determined using a plaque-forming cell (PFC) assay. Splenic lymphocytes from mice injected with delta9-THC showed a depressed immunologic response when compared with cells from control animals which were identically sensitized in vitro with sheep erythrocytes (SRBC). The direct addition of delta9-THC to the culture media altered the immunological response as demonstrated by a reduction in the number of PFC.

PubMed Disclaimer

LinkOut - more resources