Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Jan-Mar;13(1):1-6.
doi: 10.4103/2045-9912.351890.

Clinical utility of ozone therapy and hyperbaric oxygen therapy in degenerative disc disease

Affiliations
Review

Clinical utility of ozone therapy and hyperbaric oxygen therapy in degenerative disc disease

Kaitlyn Re et al. Med Gas Res. 2023 Jan-Mar.

Abstract

Ozone can be medically useful concerning healing wounds and relieving pain in various conditions, such as disc disease. The aspects of human blood ozonation have been reviewed, as well as potential complications that may arise. The mechanisms of ozone therapy are discussed in detail. It is imperative to recognize ozone as a useful proxy in oxidative-stress related diseases, consolidating other medical gases recognized for their therapeutic importance. The utility of hyperbaric oxygen therapy is also discussed. Disc herniation is very common, as more than 3 million cases are treated per year. Herein we review the medical, surgical, and gene-based therapies that ozone therapy can provide regarding disc disease.

Keywords: disc degeneration; disc disease; disc herniation; healing; hyperbaric oxygen therapy; ozone therapy; silent electron discharge.

PubMed Disclaimer

Conflict of interest statement

None

Similar articles

Cited by

References

    1. Hassett G, Hart DJ, Manek NJ, Doyle DV, Spector TD. Risk factors for progression of lumbar spine disc degeneration: the Chingford study. Arthritis Rheum. 2003;48:3112–3117. - PubMed
    1. Sicard A. Abnormalities of the lumbosacral joint. PresseMed. 1950;58:1112–1113. - PubMed
    1. Olson EJ, Hanley EN, Jr, Rudert MJ, Baratz ME. Vertebral column allografts for the treatment of segmental spine defects. An experimental investigation in dogs. Spine (Phila Pa 1976) 1991;16:1081–1088. - PubMed
    1. Hexdall E, Brave R, Kraft K, Siewers J. Diving deep into hyperbaric oxygen therapy. Nursing. 2016;46:28–36. - PubMed
    1. Lam G, Fontaine R, Ross FL, Chiu ES. Hyperbaric oxygen therapy: exploring the clinical evidence. Adv Skin Wound Care. 2017;30:181–190. - PubMed

MeSH terms