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Comment
. 2022 Oct;33(10):1954-1955.
doi: 10.1681/ASN.2022070747. Epub 2022 Aug 10.

Authors' Reply: Endopeptidase Therapy for Anti-Glomerular Basement Membrane Disease: Beware of Anti-Hinge Antibodies!

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Authors' Reply: Endopeptidase Therapy for Anti-Glomerular Basement Membrane Disease: Beware of Anti-Hinge Antibodies!

Mårten Segelmark et al. J Am Soc Nephrol. 2022 Oct.
No abstract available

Keywords: anti-GBM disease; glomerulonephritis.

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References

    1. Uhlin F, Szpirt W, Kronbichler A, Bruchfeld A, Soveri I, Rostaing L, et al. : Endopeptidase cleavage of anti-glomerular basement membrane antibodies in vivo in severe kidney disease: An open-label phase 2a study. J Am Soc Nephrol 33: 829–838, 2022 - PMC - PubMed
    1. Winstedt L, Järnum S, Nordahl EA, Olsson A, Runström A, Bockermann R, et al. : Complete removal of extracellular IgG antibodies in a randomized dose-escalation phase I study with the bacterial enzyme IdeS--A novel therapeutic opportunity. PLoS One 10: e0132011, 2015 - PMC - PubMed

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