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Case Reports
. 2022 May 18:42:50.
doi: 10.11604/pamj.2022.42.50.35120. eCollection 2022.

Vulvar Buschke-Löwenstein tumor in a HPV 16 infected woman: case report

Safia Ernez  1 , Mouna Derouich  1 , Salma Chachia  1 , Sassi Boughizane  1
Affiliations
Case Reports

Vulvar Buschke-Löwenstein tumor in a HPV 16 infected woman: case report

Safia Ernez et al. Pan Afr Med J. .

Abstract

The Buschke-Löwenstein tumor is characterized by an exophytic lesion on the perianal region. It is considered benign but there is a high risk of recurrence and degenerative potential. It is commonly associated with human papillomavirus (HPV) especially subtypes 6 and 11, its evolution depends on the host's immunity and the association with other sexually transmitted diseases. Surgical excision is the recommended treatment in most cases. We report the case of a 54-year-old woman with only diabetes history, who had verrucous vulvar lesion associated to HPV subtype 16 treated with large excision.

Keywords: Buschke Löwenstein tumor; case report; human papillomavirus; verrucous lesion.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
exophytic vulvar lesion suggestive of Buschke-Löwenstein tumor
See this image and copyright information in PMC

References

    1. O'Mahony C, Gomberg M, Skerlev M, Alraddadi A, de Las Heras-Alonso ME, Majewski S, et al. Position statement for the diagnosis and management of anogenital warts. J Eur Acad Dermatol Venereol. 2019 Jun;33(6):1006–1019. - PMC - PubMed
    1. Nieves-Condoy JF, Acuña-Pinzón CL, Chavarría-Chavira JL, Hinojosa-Ugarte D, Zúñiga-Vázquez LA. Giant condyloma acuminata (Buschke-Lowenstein Tumor): review of an unusual disease and difficult to manage (Perez-Lopez FR, éditeur) Infect Dis Obstet Gynecol. 2021 Jun 30;2021:9919446. - PMC - PubMed
    1. Chu QD, Vezeridis MP, Libbey PN, Wanebo HJ. Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions: analysis of 42 cases. Dis Colon Rectum. 1994 sept;37(9):950–7. - PubMed
    1. Valerie R, Yanofsky BS, Rita V. Patel, Gary Goldenberg. Genital Warts A Comprehensive Review. The Journal of clinical and Aesthetic Dermatology. 2012 Jun;5(6):25–36. - PMC - PubMed
    1. Mejjad AE, Dakir M, Tahiri M, Attar H, Cherkaoui A, Araki A, et al. Le condylome acuminé géant-tumeur de Buschke Lowenstein (à propos de 3 cas) Prog Urol. 2003 Jun;13(3):513–7. - PubMed

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