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Case Reports
. 2020 Sep 21;1(3):109-111.
doi: 10.14744/hf.2020.2020.0021. eCollection 2020 Sep.

A Disquiet Find: Anabolic-androgenic steroids and Vanishing Bile Duct Syndrome

Chetan Kalal  1 , Adinath Wagh  1 , Atif Patel  1 , Harshad Joshi  1 , Ravindra Surude  1 , Anil Singh  2 , Shobna Bhatia  1 , Chetan Bhatt  1
Affiliations
Case Reports

A Disquiet Find: Anabolic-androgenic steroids and Vanishing Bile Duct Syndrome

Chetan Kalal et al. Hepatol Forum. .

Abstract

A common practice among young athletes and body-builders is the adoption, use, and self-administration of androgenic anabolic steroid commonly referred to as AASs. Prime classification of these anabolic steroids is either testosterone or synthetic testosterone derivatives. They are primarily used for performance and endurance enhancement. However, the use of steroids is not without adverse effects. Steroid-induced liver diseases may range from chronic hepatitis to vascular or bile ductular injury and death. Presented herein is a case of Vanishing Bile Duct Syndrome due to the anabolic steroid consumption by a young, healthy male.

Keywords: Anabolic androgenic steroid; chronic cholestatic hepatitis; nandrolone decanoate; vanishing bile duct syndrome.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
Histologic examination of the liver. Hematoxylin and eosin (H&E) staining, original magnification X 40, showing severe biliary ductopenia with mixed infiltrates (arrow) in the portal tract.
Figure 2
Figure 2
Histologic examination of liver. Hematoxylin and eosin (H&E) staining, original magnification X 40, showing intra-hepatocytic and ductular cholestasis with bile plugs (arrow).
See this image and copyright information in PMC

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