Emerging Multiorgan Klebsiella pneumoniae Invasive Syndrome Leading to Septic Shock: A Case Report and Review of the Literature
- PMID: 35949763
- PMCID: PMC9356912
- DOI: 10.7759/cureus.26647
Emerging Multiorgan Klebsiella pneumoniae Invasive Syndrome Leading to Septic Shock: A Case Report and Review of the Literature
Abstract
Klebsiella pneumoniae (K. pneumoniae) is a community-acquired pathogen that typically causes pneumonia and urinary tract infections. Rarely, it can affect other organ systems such as the gastrointestinal tract, as well as the meninges, ears, eyes, and spine. We present the case of a 62-year-old male admitted with septic shock secondary to necrotizing pneumonia and multiple hepatic liver abscesses, which to the best of our knowledge, is the first reported case of multiorgan invasive K. pneumoniae infection, including the presence of a newly recognized syndrome referred as Invasive Liver Abscess Syndrome (ILAS). It is important to maintain both ILAS and K. pneumoniae invasive syndrome (KPIS) in the differential diagnosis, especially in areas of the world with a large number of tourists and immigrants, such as New York City, where the presented case took place.
Keywords: emerging disease; emerging pathogen; hypervirulent klebsiella pneumoniae; invasive liver abscess syndrome (ilas); klebsiella pneumoniae (kp); klebsiella pneumoniae invasive syndrome (kpis); liver abscess drainage; necrotizing pneumonia; ophthalmic septic emboli; septic shock.
Copyright © 2022, Villanueva et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
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References
-
- Community acquired Klebsiella pneumoniae, K1 serotype. Invasive liver abscess with bacteremia and endophthalmitis. Enani MA, El-Khizzi NA. https://pubmed.ncbi.nlm.nih.gov/22821314/ Saudi Med J. 2012;33:782–786. - PubMed
-
- More than meets the eye: Klebsiella pneumoniae invasive liver abscess syndrome presenting with endophthalmitis. Van Keer J, Van Keer K, Van Calster J, Derdelinckx I. J Emerg Med. 2017;52:0–3. - PubMed
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