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Case Reports
. 2022 Jun 9;13(2):429-434.
doi: 10.1159/000519914. eCollection 2022 May-Aug.

An Unusual Case of Unilateral Maculopathy

Chloe Jennifer Shipton  1 , David Francis Gilmour  1
Affiliations
Case Reports

An Unusual Case of Unilateral Maculopathy

Chloe Jennifer Shipton et al. Case Rep Ophthalmol. .

Abstract

A 44-year-old male presented with unilateral sudden onset reduced visual acuity. The optical coherence tomography (OCT) scan demonstrated submacular fluid with thickening and hyper-reflectivity of the outer retinal layers, together with subfoveal retinal pigment epithelial hyper-reflectivity corresponding to a small area of foveal interdigitation zone/ellipsoid zone (IZ/EZ) loss in the detached retina. An OCT 4 months later showed resolution of the submacular fluid, but the IZ/EZ loss persisted with thinning of the outer nuclear layer, resulting in a poor visual outcome. The clinical findings most likely represent a case of unilateral acute idiopathic maculopathy; however, the OCT features and poor visual outcome are not typical. Differential diagnoses include acute solar maculopathy, central serous chorioretinopathy, poppers maculopathy, whiplash maculopathy, and acute retinal pigment epitheliitis.

Keywords: Medical retina; Optical coherence tomography; Solar retinopathy; Submacular fluid; Unilateral acute idiopathic maculopathy.

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Conflict of interest statement

Both authors have no conflicts of interest or financial disclosures.

Figures

Fig. 1
Fig. 1
a Color fundus image of left eye at presentation. b OCT of left eye at presentation. c OCT of left eye 4 months after presentation. d OCT of fovea left eye 14 months after presentation. e OCT of RPE changes left eye 14 months after presentation.
Fig. 2
Fig. 2
a Color fundus image of right eye at presentation. b OCT of right eye at presentation.
See this image and copyright information in PMC

References

    1. Jung CS, Payne JF, Bergstrom CS, Cribbs BE, Yan J, Hubbard GB, et al. Multimodality diagnostic imaging in unilateral acute idiopathic maculopathy. Arch Ophthalmol. 2012;130((1)):50–6. - PMC - PubMed
    1. Freund KB, Yannuzzi LA, Barile GR, Spaide RF, Milewski SA, Guyer DR. The expanding clinical spectrum of unilateral acute idiopathic maculopathy. Arch Ophthalmol. 1996;114((5)):555–9. - PubMed
    1. Yannuzzi LA, Jampol LM, Rabb MF, Sorenson JA, Beyrer C, Wilcox LM. Unilateral acute idiopathic maculopathy. Arch Ophthalmol. 1991;109((10)):1411–6. - PubMed
    1. Beck AP, Jampol LM, Glaser DA, Glasser DA, Pollack JS. Is coxsackievirus the cause of unilateral acute idiopathic maculopathy? Arch Ophthalmol. 2004;122((1)):121–3. - PubMed
    1. Jorge LF, Queiroz RP, Gasparin F, Vasconcelos-Santos DV. Presumed unilateral acute idiopathic maculopathy following H1N1 vaccination. Ocul Immunol Inflamm. 2021 Aug 18;29((6)):1151–3. - PubMed

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