Urothelial Carcinoma in an Allograft kidney
- PMID: 35950049
- PMCID: PMC9247438
- DOI: 10.1159/000524901
Urothelial Carcinoma in an Allograft kidney
Abstract
Patients who have been kidney transplanted have an increased risk of developing cancer. This case report presents a rarely described case in which a patient, who had received a kidney transplant from a deceased donor, was diagnosed with disseminated urothelial carcinoma originating from the allograft. After the removal of the allograft and the immunosuppressive treatment, there was regression in the cancer. Unfortunately, it was not a complete regression of the urothelial cancer and the patient died. This case indicates that there is a risk of getting cancer from the transplanted kidney from a deceased donor, but also that the immunosuppressive treatment can contribute to the development of this cancer.
Keywords: Case report; Donor; Immunosuppressive treatment; Kidney transplant; Urothelial carcinoma.
Copyright © 2022 by S. Karger AG, Basel.
Conflict of interest statement
The authors have no conflicts of interest to declare.
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References
-
- Vajdic CM, McDonald SP, McCredie MRE, van Leeuwen MT, Stewart JH, Law M, et al. Cancer incidence before and after kidney transplantation. JAMA. 2006 Dec 20;296((23)):2823–31. - PubMed
-
- Villeneuve PJ, Schaubel DE, Fenton SS, Shepherd FA, Jiang Y, Mao Y. Cancer incidence among Canadian kidney transplant recipients. Am J Transplant. 2007 Apr 1;7((4)):941–8. - PubMed
-
- Hernández-Gaytán CA, Rodríguez-Covarrubias F, Castillejos-Molina RA, Hernández-Porras A, Tobia I, Dubin JM, et al. Urological cancers and kidney transplantation: a literature review. Curr Urol reports. 2021;22((12)):62. - PubMed
-
- Leon G, Szabla N, Boissier R, Gigante M, Caillet K, Verhoest G, et al. Kidney graft urothelial carcinoma: results from a multicentric retrospective national study. Urology. 2020 Jan 1;135:101–5. - PubMed
-
- Debout A, Foucher Y, Trébern-Launay K, Legendre C, Kreis H, Mourad G, et al. Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation. Kidney Int. 2015 Feb 3;87((2)):343–9. - PubMed
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