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. 2022 Aug 11;17(8):e0272333.
doi: 10.1371/journal.pone.0272333. eCollection 2022.

Intra- and post-operative risk of retinal breaks during vitrectomy for macular hole and vitreomacular traction

Neil K Jairath  1 , Yannis M Paulus  1   2 , Angela Yim  1 , Yunshu Zhou  1 , Bela J Parekh  1 , Ruple Jairath  1 , David C Musch  1   3 , Julie M Rosenthal  1
Affiliations

Intra- and post-operative risk of retinal breaks during vitrectomy for macular hole and vitreomacular traction

Neil K Jairath et al. PLoS One. .

Abstract

Background/objective: To evaluate the development of intra- and post-operative retinal breaks after pars plana vitrectomy (PPV) for macular hole (MH) and/or vitreomacular traction (VMT).

Subjects/methods: Medical records of patients who underwent PPV at Kellogg Eye Center between 1/1/2005-6/30/2018, were evaluated in three groups: group 1, MH/VMT (n = 136); group 2, epiretinal membrane (ERM) without VMT (n = 270); and group 3, diagnostic vitrectomy (DV) or vitreous opacities (n = 35). Statistical analyses were conducted using SAS.

Results: 20.6% of patients with MH/VMT, 8.5% of patients with ERM, and 5.7% of patients with DV or vitreous opacities had either intra-operative or post-operative breaks. Indication of MH/VMT versus ERM was a significant predictor for this outcome (p = .0112). The incidence of retinal breaks was higher in operations using 23-gauge versus 25-gauge PPV (25.0% vs. 7.4%, p < .0001).

Conclusions: The presence of MH and/or VMT is a significant risk factor for retinal breaks from PPV, as is use of 23-gauge vitrectomy.

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Conflict of interest statement

The authors have declared the no competing interests exist.

Figures

Fig 1
Fig 1. Flow diagram detailing exclusion criteria for the patients acquired in the study, including numbers of patient records removed at each exclusion step that led to curation of the final group of patient records included in the analysis.
Of 2,912 patient records retrieved with the initial search strategy, 441 were included in the study.
See this image and copyright information in PMC

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