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Comment
. 2022 Nov;18(11):681-682.
doi: 10.1038/s41581-022-00622-8.

A polygenic score predicts CKD across ancestries

Inga Steinbrenner  1 , Anna Köttgen  2
Affiliations
Comment

A polygenic score predicts CKD across ancestries

Inga Steinbrenner et al. Nat Rev Nephrol. 2022 Nov.
No abstract available

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Comment on

  • Genome-wide polygenic score to predict chronic kidney disease across ancestries.
    Khan A, Turchin MC, Patki A, Srinivasasainagendra V, Shang N, Nadukuru R, Jones AC, Malolepsza E, Dikilitas O, Kullo IJ, Schaid DJ, Karlson E, Ge T, Meigs JB, Smoller JW, Lange C, Crosslin DR, Jarvik GP, Bhatraju PK, Hellwege JN, Chandler P, Torvik LR, Fedotov A, Liu C, Kachulis C, Lennon N, Abul-Husn NS, Cho JH, Ionita-Laza I, Gharavi AG, Chung WK, Hripcsak G, Weng C, Nadkarni G, Irvin MR, Tiwari HK, Kenny EE, Limdi NA, Kiryluk K. Khan A, et al. Nat Med. 2022 Jul;28(7):1412-1420. doi: 10.1038/s41591-022-01869-1. Epub 2022 Jun 16. Nat Med. 2022. PMID: 35710995 Free PMC article.

References

    1. Eckardt, K. U. et al. Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 382, 158–169 (2013). - DOI
    1. Lambert, S. A. et al. The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation. Nat. Genet. 53, 420–425 (2021). - DOI
    1. Martin, A. R. et al. Clinical use of current polygenic risk scores may exacerbate health disparities. Nat. Genet. 51, 584–591 (2019). - DOI
    1. Khan, A. et al. Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nat. Med. 28, 1412–1420 (2022). - DOI
    1. Wand, H. et al. Improving reporting standards for polygenic scores in risk prediction studies. Nature 591, 211–219 (2021). - DOI

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