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. 2022 Jul 27;27(15):4812.
doi: 10.3390/molecules27154812.

Efficacy of Biologically Active Food Supplements for People with Atherosclerotic Vascular Changes

Natalia Pleshkova  1 , Boisjoni Tokhiriyon  2 , Andrei Vekovtsev  3 , Valeriy Mikhailovich Poznyakovsky  4   5 , Valentina Lapina  2 , Madina Atlaevna Takaeva  6 , Vladimir Nikolaevich Sorokopudov  7 , Elena Valeryevna Karanina  8
Affiliations

Efficacy of Biologically Active Food Supplements for People with Atherosclerotic Vascular Changes

Natalia Pleshkova et al. Molecules. .

Abstract

The current paper deals with the development of a new biologically active food supplement (BAFS) aimed at treating atherosclerosis. Since atherosclerosis is considered to be a disease of aging, the composition of the supplement includes such essential minerals as magnesium and potassium, which are commonly used to prevent atherosclerosis, as well as vitamins C, E and the B-group vitamins in order to address the needs of the elderly. The authors outline the supplement-manufacturing technology and discuss the clinical trial undertaken by patients, aged about 60 years, with peripheral atherosclerosis. The research methodology focuses on studying the effectiveness of the developed supplement by assessing the influence of the active ingredients on treating metabolic disorders. To establish the efficacy of the supplement, blood tests, ultrasound and physical examinations were applied. The combination therapy resulted in improved metabolism and an overall better performance of the cardiovascular system; therefore, the BASF can be recommended as part of combination therapy to prevent and treat atherosclerotic and age-related changes in blood vessels.

Keywords: BAFS; combination therapy; efficacy; functional foods; peripheral atherosclerosis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Mechanism of the food supplement influence on improving metabolism disorders in people with peripheral atherosclerosis.
See this image and copyright information in PMC

References

    1. WHO . Report on Non-Infectious Diseases Situation in the World—Executive Summary. World Health Organization; Geneva, Switzerland: 2011. pp. 14–21.
    1. Bokeria L.A. Russia’s Health: Atlas. 8th ed. Russia’s Academy of Sciences; Moscow, Russia: 2012. pp. 386–400. Bakoulev Centre for Cardiovascular Surgery.
    1. Aronov D.M. Atherosclerosis: Treatment and Prevention—Monograph. Triada-X; Moscow, Russia: 2000. pp. 127–144. (In Russian)
    1. Karpov R.C. In: Atherosclerosis, Pathogenesis, Clinical Findings, Functional Diagnostics and Treatment—Monograph. Karpov R.C., Dudko V.A., editors. STT; Tomsk, Russia: 1998. pp. 553–579.
    1. Kullo I.J., Ballantyne C.M. Conditional risk factors for atherosclerosis. Mayo Clin. Proc. 2005;80:219–230. doi: 10.4065/80.2.219. - DOI - PubMed