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Case Reports
. 2022 Aug 9;10(8):e6214.
doi: 10.1002/ccr3.6214. eCollection 2022 Aug.

Status epilepticus and the presence of SARS-COV-2 in the cerebrospinal fluid: A case report

Sara Abdolahi  1 , Rezan Ashayeri Ahmadabad  1 , Ali Gorji  1   2   3   4 , Zahra Mirzaasgari  1   5
Affiliations
Case Reports

Status epilepticus and the presence of SARS-COV-2 in the cerebrospinal fluid: A case report

Sara Abdolahi et al. Clin Case Rep. .

Abstract

A growing number of studies indicate a broad range of neurological manifestations, including seizures, occur in patients with COVID-19 infection. We report a 29-year-old female patient with status epilepticus and positive SARS-CoV-2 in the cerebrospinal fluid. Our findings support previous reports suggesting seizure as a possible symptom of COVID-19 infection.

Keywords: COVID‐19 infection; neuroinvasive; seizure.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Coronal T2‐weighted Flair non‐contrast brain magnetic resonance imaging (MRI) (A) and coronal T1‐weighted contrast‐enhanced brain MRI (B)
FIGURE 2
FIGURE 2
EEG showed bilateral temporal epileptiform discharges
See this image and copyright information in PMC

References

    1. Paramasivam A, Priyadharsini JV, Raghunandhakumar S, Elumalai P. A novel COVID‐19 and its effects on cardiovascular disease. Hypertens Res. 2020;43(7):729‐730. - PMC - PubMed
    1. Guerrero JI, Barragán LA, Martínez JD, et al. Central and peripheral nervous system involvement by COVID‐19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings. BMC Infect Dis. 2021;21(1):1‐5. - PMC - PubMed
    1. Huang J, Zheng M, Tang X, Chen Y, Tong A, Zhou L. Potential of SARS‐CoV‐2 to cause CNS infection: biologic fundamental and clinical experience. Front Neurol. 2020;18(11):659. - PMC - PubMed
    1. Septyaningtrias DE, Susilowati R. Neurological involvement of COVID‐19: from neuroinvasion and neuroimmune crosstalk to long‐term consequences. Rev Neurosci. 2021;32:427‐442. - PubMed
    1. Rezaeitalab F, Jamehdar SA, Sepehrinezhad A, et al. Detection of SARS‐coronavirus‐2 in the central nervous system of patients with severe acute respiratory syndrome and seizures. J Neurovirol. 2021;27(2):348‐353. - PMC - PubMed

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