Expert consensus on perioperative treatment for non-small cell lung cancer

Jianchun Duan^#¹, Fengwei Tan^#², Nan Bi³, Chun Chen⁴, Ke-Neng Chen⁵, Ying Cheng⁶, Qian Chu⁷, Di Ge⁸, Jie Hu^{9

10}, Yunchao Huang¹¹, Tao Jiang¹², Hao Long¹³, You Lu¹⁴, Meiqi Shi¹⁵, Jialei Wang¹⁶, Qiming Wang¹⁷, Fan Yang¹⁸, Nong Yang¹⁹, Yu Yao²⁰, Jianming Ying²¹, Caicun Zhou²², Qing Zhou²³, Qinghua Zhou²⁴, Stefano Bongiolatti²⁵, Alessandro Brunelli²⁶, Alfonso Fiorelli²⁷, Elisa Gobbini²⁸, Cesare Gridelli²⁹, Thomas John³⁰, Jae Jun Kim³¹, Steven H Lin³², Giulio Metro³³, Fabrizio Minervini³⁴, Nuria M Novoa³⁵, Dwight H Owen³⁶, Maria Rodriguez³⁷, Ichiro Sakanoue³⁸, Marco Scarci³⁹, Kenichi Suda⁴⁰, Fabrizio Tabbò⁴¹, Terence Chi Chun Tam⁴², Masanori Tsuchida⁴³, Junji Uchino^{44

45}, Luca Voltolini²⁵, Jie Wang^#¹, Shugeng Gao^#²

Affiliations

¹ Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
² Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
³ Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
⁴ Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
⁵ Department of Thoracic Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China.
⁶ Department of Medical Oncology, Jilin Cancer Hospital, Changchun, China.
⁷ Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
⁸ Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
⁹ Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
¹⁰ Shanghai Geriatric Center, Shanghai, China.
¹¹ Department of Thoracic Surgery I, Key Laboratory of Lung Cancer of Yunnan Province, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Cancer Center of Yunnan Province, Kunming, China.
¹² Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
¹³ State Key Laboratory of Oncology in Southern China, Department of Thoracic Surgery, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
¹⁴ Department of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
¹⁵ Department of Medical Oncology, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
¹⁶ Department of Thoracic Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
¹⁷ Department of Medical Oncology, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
¹⁸ Department of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
¹⁹ Department of Lung Cancer and Gastroenterology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
²⁰ Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
²¹ Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
²² Department of Medical Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
²³ Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
²⁴ Lung Cancer Institute/Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
²⁵ Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy.
²⁶ Department of Thoracic Surgery, St. James's University Hospital, Leeds, UK.
²⁷ Thoracic Surgery Unit, Universitàdella Campania Luigi Vanvitelli, Naples, Italy.
²⁸ Department of Thorax, University of Grenoble, CHU Grenoble-Alpes, La Tronche, France.
²⁹ Division of Medical Oncology, "S. G. Moscati" Hospital, Avellino, Italy.
³⁰ Department of Medical Oncology, Peter MacCallum Cancer Center 305 Grattan St, Melbourne, Australia.
³¹ Department of Thoracic and Cardiovascular Surgery, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Republic of Korea.
³² Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³³ Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
³⁴ Department of Thoracic Surgery, Cantonal Hospital Lucerne, Lucerne, Switzerland.
³⁵ University Hospital of Salamanca and Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
³⁶ Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
³⁷ Department of Thoracic Surgery, Clinica Universidad de Navarra, Madrid, Spain.
³⁸ Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
³⁹ Department of Cardiothoracic Surgery, Imperial College Healthcare NHS Trust, London, UK.
⁴⁰ Division of Thoracic Surgery, Department of Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
⁴¹ Department of Oncology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.
⁴² Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
⁴³ Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
⁴⁴ Department of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
⁴⁵ Bannan Central Hospital, Iwata, Shizuoka, Japan.

^# Contributed equally.

PMID: 35958323
PMCID: PMC9359944
DOI: 10.21037/tlcr-22-527

Review

Expert consensus on perioperative treatment for non-small cell lung cancer

Jianchun Duan et al. Transl Lung Cancer Res. 2022 Jul.

. 2022 Jul;11(7):1247-1267.

doi: 10.21037/tlcr-22-527.

Authors

Affiliations

¹ Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
² Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
³ Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
⁴ Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
⁵ Department of Thoracic Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China.
⁶ Department of Medical Oncology, Jilin Cancer Hospital, Changchun, China.
⁷ Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
⁸ Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
⁹ Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
¹⁰ Shanghai Geriatric Center, Shanghai, China.
¹¹ Department of Thoracic Surgery I, Key Laboratory of Lung Cancer of Yunnan Province, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Cancer Center of Yunnan Province, Kunming, China.
¹² Department of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
¹³ State Key Laboratory of Oncology in Southern China, Department of Thoracic Surgery, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
¹⁴ Department of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
¹⁵ Department of Medical Oncology, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
¹⁶ Department of Thoracic Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
¹⁷ Department of Medical Oncology, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
¹⁸ Department of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
¹⁹ Department of Lung Cancer and Gastroenterology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
²⁰ Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
²¹ Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
²² Department of Medical Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
²³ Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
²⁴ Lung Cancer Institute/Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
²⁵ Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy.
²⁶ Department of Thoracic Surgery, St. James's University Hospital, Leeds, UK.
²⁷ Thoracic Surgery Unit, Universitàdella Campania Luigi Vanvitelli, Naples, Italy.
²⁸ Department of Thorax, University of Grenoble, CHU Grenoble-Alpes, La Tronche, France.
²⁹ Division of Medical Oncology, "S. G. Moscati" Hospital, Avellino, Italy.
³⁰ Department of Medical Oncology, Peter MacCallum Cancer Center 305 Grattan St, Melbourne, Australia.
³¹ Department of Thoracic and Cardiovascular Surgery, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Republic of Korea.
³² Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³³ Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
³⁴ Department of Thoracic Surgery, Cantonal Hospital Lucerne, Lucerne, Switzerland.
³⁵ University Hospital of Salamanca and Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
³⁶ Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
³⁷ Department of Thoracic Surgery, Clinica Universidad de Navarra, Madrid, Spain.
³⁸ Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
³⁹ Department of Cardiothoracic Surgery, Imperial College Healthcare NHS Trust, London, UK.
⁴⁰ Division of Thoracic Surgery, Department of Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
⁴¹ Department of Oncology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.
⁴² Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
⁴³ Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
⁴⁴ Department of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
⁴⁵ Bannan Central Hospital, Iwata, Shizuoka, Japan.

^# Contributed equally.

PMID: 35958323
PMCID: PMC9359944
DOI: 10.21037/tlcr-22-527

No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tlcr.amegroups.com/article/view/10.21037/tlcr-22-527/coif). CZ serves as an Editor-in-Chief of Translational Lung Cancer Research from August 2014 to July 2022. SHL serves as an unpaid editorial board member of Translational Lung Cancer Research from September 2019 to September 2023. GM serves as an unpaid editorial board member of Translational Lung Cancer Research from February 2016 to July 2023. CG serves as an unpaid editorial board member of Translational Lung Cancer Research from September 2019 to September 2023, and received honoraria as speaker bureau or advisory board member or consulting fees form Menarini, Roche, Eli Lilly, Boehringer, Amgen, Pfizer, Novartis, MSD, BMS, Astra Zeneca, Takeda, Novartis, GSK, Karyopharm. Qing Z received lecture and presentations fees from AstraZeneca, Boehringer Ingelheim, BMS, Eli Lilly, MSD, Pfizer, Roche, and Sanofi. AB received consulting fees as an Advisory Board with Astra Zeneca, BD, Ethicon, Medtronic, Roche, and is the president of European Society of Thoracic Surgeons. TJ received consulting fees from Roche, Merck, MSD, Puma, AstraZeneca, BMS, Amgen, Gilead, Specialised Therapeutics. DHO reports research funding (to institution) from Genentech, BMS, Merck, Pfizer, Palobiofarma, and Onc. AI. MR received honoraria for lectures and expert meetings from Astrazeneca, and also received honoraria for lectures and expert meetings as well as travel expenses from Abex. KS received a research grant from Boehringer-Ingelheim, through Kindai University Faculty of Medicine, has received consulting fees from AstraZeneca, and has received honoraria from Chugai, Taiho, and AstraZeneca. FT received speaker bureau from AstraZeneca. The other authors have no conflicts of interest to declare.

Comment in

The path forward in early-stage lung cancer.
Cuppens K, Baas P. Cuppens K, et al. Transl Lung Cancer Res. 2023 Jan 31;12(1):11-13. doi: 10.21037/tlcr-22-546. Epub 2022 Dec 30. Transl Lung Cancer Res. 2023. PMID: 36762062 Free PMC article. No abstract available.

References

1. Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2022. CA Cancer J Clin 2022;72:7-33. 10.3322/caac.21708 - DOI - PubMed
1. Melzer AC, Triplette M. Screening high risk populations for lung cancer. BMJ 2022;376:o666. 10.1136/bmj.o666 - DOI - PubMed
1. Kehl KL, Zahrieh D, Yang P, et al. Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy Among Patients With Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216). JAMA Oncol 2022;8:717-28. 10.1001/jamaoncol.2022.0039 - DOI - PMC - PubMed
1. Pignon JP, Tribodet H, Scagliotti GV, et al. Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group. J Clin Oncol 2008;26:3552-9. 10.1200/JCO.2007.13.9030 - DOI - PubMed
1. NSCLC Meta-analysis Collaborative Group . Preoperative chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual participant data. Lancet 2014;383:1561-71. 10.1016/S0140-6736(13)62159-5 - DOI - PMC - PubMed

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Expert consensus on perioperative treatment for non-small cell lung cancer

Affiliations

Expert consensus on perioperative treatment for non-small cell lung cancer

Authors

Affiliations

Conflict of interest statement

Comment in

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