Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jul 25:10:926058.
doi: 10.3389/fpubh.2022.926058. eCollection 2022.

Timely Estimates of 5-Year Relative Survival for Patients With Cervical Cancer: A Period Analysis Using Cancer Registry Data From Taizhou, Eastern China

Hongsheng Lu  1 , Lu Li  2 , Yongran Cheng  3 , Zhaohui Yang  1 , Xuequan Cao  1 , Hui Zhang  1 , Dongju Qiao  4 , Liangyou Wang  4 , Tianhui Chen  5   6   7
Affiliations

Timely Estimates of 5-Year Relative Survival for Patients With Cervical Cancer: A Period Analysis Using Cancer Registry Data From Taizhou, Eastern China

Hongsheng Lu et al. Front Public Health. .

Abstract

Objectives: While timely assessment of long-term survival for patients with cervical cancer is essential for the evaluation of early detection and screening programs for cervical cancer, those data are extremely scarce in China. We aimed to timely and accurately assess long-term survival for patients with cervical cancer in eastern China, using cancer registry data from Taizhou, eastern China.

Methods: Patients diagnosed with cervical cancer during 2004-2018 from four cancer registries with high-quality data from Taizhou, eastern China were included. A period analysis was used to calculate the 5-year relative survival (RS) overall and on stratification by sex, age at diagnosis, and region. Additionally, the projected 5-year relative survival (RS) of patients with cervical cancer during 2019-2023 was evaluated, using a model-based period analysis.

Results: Overall 5-year RS for patients with cervical cancer during 2014-2018 reached 90.9%. When stratified by age at diagnosis, we found a clear age gradient for 5-year RS, declining from 95.6% for age <45 years to 68.7% for age >74 years, while urban areas had higher 5-year RS compared to rural areas (92.9 vs. 88.6%). We found a clear increasing trend of 5-year RS during 2004-2018 overall and on stratification by region and age at diagnosis. The projected overall 5-year RS is expected to reach 94.2% for the period 2019-2023.

Conclusions: We found that, for the first time in China, using period analysis, the most up-to-date (during 2014-2018) 5-year RS for patients with cervical cancer reached 90.9%. Our data have important implications for the timely evaluation of early detection and screening programs for patients with cervical cancer in eastern China.

Keywords: 5-year relative survival; cancer registry; cervical cancer; period analysis; survival.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of this study.
Figure 2
Figure 2
Trends of 5-year relative survival for patients with cervical cancer from Taizhou, eastern China during 2004–2008, 2009–2013, 2014–2018, and 2019–2023 by region (urban areas vs. rural areas).
Figure 3
Figure 3
Trends of 5-year relative survival for patients with cervical cancer from Taizhou, eastern China during 2004–2008, 2009–2013, 2014–2018, and 2019–2023 by age at diagnosis.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Chen T, Brenner H, Fallah M, Jansen L. Risk of second primary cancers in women diagnosed with endometrial cancer in German and Swedish cancer registries. Int J Cancer. (2017) 141:2270–80. 10.1002/ijc.30930 - DOI - PubMed
    1. Zeng H, Chen W, Zheng R, Zhang S, Ji JS, Zou X, et al. . Changing cancer survival in China during 2003–15: a pooled analysis of 17 population-based cancer registries. Lancet Glob Health. (2018) 6:e555–67. 10.1016/S2214-109X(18)30127-X - DOI - PubMed
    1. Benedetti Panici P, Basile S, Angioli R. Pelvic and aortic lymphadenectomy in cervical cancer: the standardization of surgical procedure and its clinical impact. Gynecol Oncol. (2009) 113:284–90. 10.1016/j.ygyno.2008.12.014 - DOI - PubMed
    1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. (2018) 68:394–424. 10.3322/caac.21492 - DOI - PubMed
    1. Li S, Hu T, Lv W, Zhou H, Li X, Yang R, et al. . Changes in prevalence and clinical characteristics of cervical cancer in the People's Republic of China: a study of 10,012 cases from a nationwide working group. Oncologist. (2013) 18:1101–7. 10.1634/theoncologist.2013-0123 - DOI - PMC - PubMed

Publication types